Alzheimer's disease (AD) research has entered a new era with the recent positive phase 3
clinical trials of the anti-Aβ antibodies lecanemab and donanemab. Why did it take 30 years …

Solid-like protein deposits found in aged and diseased human brains have revealed a
relationship between insoluble protein accumulations and the resulting deficits in neurologic …

Tau protein aggregates in several neurodegenerative disorders, referred to as tauopathies.
The tau isoforms observed in post mortem human brain aggregates is used to classify …

Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

The term “neurodegenerative diseases”(NDs) identifies a group of heterogeneous diseases
characterized by progressive loss of selectively vulnerable populations of neurons, which …

Oxidative damage in the brain is one of the earliest drivers of pathology in Alzheimer's
disease (AD) and related dementias, both preceding and exacerbating clinical symptoms. In …

Dynamically organized chromatin complexes often involve multiplex chromatin interactions
and sometimes chromatin-associated RNA,–. Chromatin complex compositions change …

Tauopathies are a diverse group of progressive and fatal neurodegenerative diseases
characterized by aberrant tau inclusions in the central nervous system. Tau protein forms …

The organization and coordination of fish schools provide a valuable model to investigate
the genetic architecture of affiliative behaviours and dissect the mechanisms underlying …

Background Ovarian cancer (OC) is a common tumor of the female reproductive system,
while Alzheimer's disease (AD) is a prevalent neurodegenerative disease that primarily …