Bridging smart nanosystems with clinically relevant models and advanced imaging for precision drug delivery
Q Zhou, Q Liu, Y Wang, J Chen, O Schmid… - Advanced …, 2024 - Wiley Online Library
Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or
solid tumors has entered the era of precision medicine that requires systematic knowledge …
solid tumors has entered the era of precision medicine that requires systematic knowledge …
Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases
W Balestri, R Sharma, VA da Silva, BC Bobotis… - Journal of …, 2024 - Springer
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …
caused by the interaction of genetic, environmental, and familial factors. These diseases …
Meta-analysis of the make-up and properties of in vitro models of the healthy and diseased blood–brain barrier
In vitro models of the human blood–brain barrier (BBB) are increasingly used to develop
therapeutics that can cross the BBB for treating diseases of the central nervous system. Here …
therapeutics that can cross the BBB for treating diseases of the central nervous system. Here …
Advances in the knowledge and therapeutics of schizophrenia, major depression disorder, and bipolar disorder from human brain organoid research
R Villanueva - Frontiers in Psychiatry, 2023 - frontiersin.org
Tridimensional cultures of human induced pluripotent cells (iPSCs) experimentally directed
to neural differentiation, termed “brain organoids” are now employed as an in vitro assay that …
to neural differentiation, termed “brain organoids” are now employed as an in vitro assay that …
On-chip physiological mimicry of neurovascular unit: challenges and perspectives
Neurological disorders including neurodegenerative diseases, brain tumors, and stroke are
the second leading cause of death and the greatest cause of disability worldwide. However …
the second leading cause of death and the greatest cause of disability worldwide. However …
Reconstitution of human tissue barrier function for precision and personalized medicine
Tissue barriers in a body, well known as tissue-to-tissue interfaces represented by
endothelium of the blood vessels or epithelium of organs, are essential for maintaining …
endothelium of the blood vessels or epithelium of organs, are essential for maintaining …
Engineering brain-on-a-chip platforms
The increasing prevalence of neurological and psychiatric diseases, such as Alzheimer
disease and schizophrenia, necessitates the development of new research tools to …
disease and schizophrenia, necessitates the development of new research tools to …
[HTML][HTML] Advances and Challenges of Bioassembly Strategies in Neurovascular In Vitro Modeling: An Overview of Current Technologies with a Focus on Three …
S Mancuso, A Bhalerao… - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Bioassembly encompasses various techniques such as bioprinting, microfluidics, organoids,
and self-assembly, enabling advances in tissue engineering and regenerative medicine …
and self-assembly, enabling advances in tissue engineering and regenerative medicine …
神经血管单元的片上生理模拟: 挑战与展望
SI Ahn, YT Kim - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Neurological disorders including neurodegenerative diseases, brain tumors, and stroke are
the second leading cause of death and the greatest cause of disability worldwide. However …
the second leading cause of death and the greatest cause of disability worldwide. However …