[HTML][HTML] Iridoid derivatives as anticancer agents: an updated review from 1970–2022
Simple Summary Cancer is one of the leading causes of death around the world. The
current treatment strategies, especially chemotherapy, have significant side effects. As a …
current treatment strategies, especially chemotherapy, have significant side effects. As a …
[HTML][HTML] Herbals and plants in the treatment of pancreatic cancer: A systematic review of experimental and clinical studies
JK Triantafillidis, E Triantafyllidi, M Sideris, T Pittaras… - Nutrients, 2022 - mdpi.com
Background: Pancreatic cancer represents the most lethal malignancy among all digestive
cancers. Despite the therapeutic advances achieved during recent years, the prognosis of …
cancers. Despite the therapeutic advances achieved during recent years, the prognosis of …
[HTML][HTML] Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the PDGFRA/MEK/ERK signaling pathway
X Liu, Y Hu, Z Xue, X Zhang, X Liu, G Liu… - Journal of Translational …, 2023 - Springer
Background Valtrate, a natural compound isolated from the root of Valeriana, exhibits
antitumor activity in many cancers through different mechanisms. However, its efficacy for …
antitumor activity in many cancers through different mechanisms. However, its efficacy for …
[HTML][HTML] Mechanism of Valeriana Jatamansi Jones for the treatment of spinal cord injury based on network pharmacology and molecular docking
Y Wang, J Lu, H Xiao, L Ding, Y He, C Chang, W Wang - Medicine, 2023 - journals.lww.com
Spinal cord injury (SCI) is characterized by high rates of disability and death. Valeriana
jatamansi Jones (VJJ), a Chinese herbal medicine, has been identified to improve motor …
jatamansi Jones (VJJ), a Chinese herbal medicine, has been identified to improve motor …
Enantioselective Synthesis of Spiro‐oxiranes: An Asymmetric Addition/Aldol/Spirocyclization Domino Cascade
KL Choo, B Mirabi, KZ Demmans… - Angewandte …, 2021 - Wiley Online Library
Enantioenriched spiro‐oxiranes bearing three contiguous stereocenters were synthesized
using a rhodium‐catalyzed asymmetric addition/aldol/spirocyclization sequence. Starting …
using a rhodium‐catalyzed asymmetric addition/aldol/spirocyclization sequence. Starting …
Pine pollen polysaccharides promote cell proliferation and accelerate wound healing by activating the JAK2-STAT3 signaling pathway
C Wang, H Shang, W Cui, F Zhou, S Zhang… - International Journal of …, 2022 - Elsevier
Natural medicine can be used to develop wound healing agents due to its excellent
characteristics of promoting rapid wound healing. Pine pollen polysaccharides (PPPS), a …
characteristics of promoting rapid wound healing. Pine pollen polysaccharides (PPPS), a …
Research progress in the ethnopharmacology, phytochemistry, pharmacology, toxicology, and quality control of Valeriana jatamansi Jones
Z Wang, Y Shi, X Zhang, J Sun, D Guo, F Luan… - Journal of …, 2024 - Elsevier
Highlights•Valeriana jatamansi Jones is widely used in traditional Chinese medicine (TCM)
and traditional Indian medicine (TIM).•The botanical, ethnopharmacological, phytochemical …
and traditional Indian medicine (TIM).•The botanical, ethnopharmacological, phytochemical …
Secondary metabolites from the underground parts of Valeriana sisymbriifolia Vahl. and their in vitro cytotoxic activities
M Erdoğan, B Aru, ŞT Yılmaz, E Yeşilada… - Phytochemistry, 2023 - Elsevier
Cytotoxic activity-guided isolation studies on the underground parts of Valeriana
sisymbriifolia Vahl. led to the isolation of 12 secondary metabolites including two …
sisymbriifolia Vahl. led to the isolation of 12 secondary metabolites including two …
Activity‐Guided Isolation of Cytotoxic Non‐Glycosidic Ester Iridoids from Valeriana alliariifolia Adams and Unravelling Their Cell Death Mechanisms
M Erdoğan, B Aru, UC Tayğun, C Şimşek… - Chemistry & …, 2022 - Wiley Online Library
The aim of this study was to isolate the cytotoxic compounds from V. alliariifolia via activity‐
guided isolation and to determine the mechanism of actions of the most potent ones. The …
guided isolation and to determine the mechanism of actions of the most potent ones. The …
Valtrate antagonizes malignant phenotypes of lung cancer cells by reducing SLC7A11
W Xu, H Yu - Human & Experimental Toxicology, 2022 - journals.sagepub.com
Objectives This research explored the efficacy of valtrate (Val) in lung cancer (LC). Methods
A549 and H1299 cells were dealt with Val. SLC7A11 was overexpressed by cell …
A549 and H1299 cells were dealt with Val. SLC7A11 was overexpressed by cell …