Osteoblasts are inherently programmed to repel sensory innervation

L Leitão, E Neto, F Conceição, A Monteiro, M Couto… - Bone research, 2020 - nature.com
Tissue innervation is a complex process controlled by the expression profile of signaling
molecules secreted by tissue-resident cells that dictate the growth and guidance of axons …

Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance

TMM Saez, I Fernandez Bessone… - …, 2020 - journals.biologists.com
Endocannabinoids (eCB) modulate growth cone dynamics and axonal pathfinding through
the stimulation of cannabinoid type-1 receptors (CB1R), the function of which depends on …

Why chronic cough in children is different

A Kantar, M Seminara - Pulmonary Pharmacology & Therapeutics, 2019 - Elsevier
Recently, there have been robust changes in our knowledge of the neurophysiology of
cough and novel clinical etiologies. Specifically, cough hypersensitivity in adults and …

A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance

A Dumoulin, NH Wilson, KL Tucker… - Development, 2024 - journals.biologists.com
Ciliopathies are characterized by the absence or dysfunction of primary cilia. Despite the fact
that cognitive impairments are a common feature of ciliopathies, how cilia dysfunction affects …

A model of tension-induced fiber growth predicts white matter organization during brain folding

KE Garcia, X Wang, CD Kroenke - Nature communications, 2021 - nature.com
The past decade has experienced renewed interest in the physical processes that fold the
developing cerebral cortex. Biomechanical models and experiments suggest that growth of …

Targeting netrin‐3 in small cell lung cancer and neuroblastoma

S Jiang, M Richaud, P Vieugué, N Rama… - EMBO Molecular …, 2021 - embopress.org
The navigation cue netrin‐1 is well‐documented for its key role in cancer development and
represents a promising therapeutic target currently under clinical investigation. Phase 1 and …

Smart coating by thermo-sensitive Pluronic F-127 for enhanced corneal healing via delivery of biological macromolecule progranulin

D Yan, W Ouyang, J Lin, Z Liu - International Journal of Biological …, 2023 - Elsevier
As a leading cause of vision impairment and blindness, corneal alkali burns lead to long-
term visual deterioration or even permanent visual impairment while effective treatment …

Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain

R Tsuchimochi, K Yamagami, N Kubo, N Amimoto… - Stem Cell Reports, 2023 - cell.com
Cell replacement therapy is expected as a new and more radical treatment against brain
damage. We previously reported that transplanted human cerebral organoids extend their …

Stick around: cell–cell adhesion molecules during neocortical development

D de Agustín-Durán, I Mateos-White, J Fabra-Beser… - Cells, 2021 - mdpi.com
The neocortex is an exquisitely organized structure achieved through complex cellular
processes from the generation of neural cells to their integration into cortical circuits after …

MicroRNA-30b-5p functions as a metastasis suppressor in colorectal cancer by targeting Rap1b

M Fan, X Ma, F Wang, Z Zhou, J Zhang, D Zhou… - Cancer Letters, 2020 - Elsevier
Colorectal liver metastasis (CRLM) is the leading cause of death in patients with colorectal
cancer (CRC). MiR-30b-5p can function as an oncogene or tumor suppressor in cancers, but …