Immunodominance in CD8+ T cell responses against Listeria monocytogenes is a well-
recognized but still not fully understood phenomenon. From listeriolysin, the major virulence …

The realistic prospect of developing a vaccine for the treatment or prevention of colon cancer
derives from recent advances in molecular biology and a better understanding of the host …

Objective To examine the influence of change in antiretroviral therapy (ART) on patterns of
CD8 T cell clonal dominance in HIV-infected children. Design Seventeen HIV-infected …

Objective: To assess whether weakly recognized epitope variants induce anergy in HIV-1-
specific CD8+ T lymphocyte (CTL) clones as a mechanism of dysfunction. Design: HIV-1 …

Although it is a sound conceptual rationale that immune pressure exerted by cytotoxic T
lymphocytes contributes towards the long-term evolution of genetically stable viruses, a …

Infection of H-2 b mice with lymphocytic choriomeningitis virus (LCMV) generates an H-2Db-
restricted cytotoxic T-lymphocyte (CTL) response whose subdominant component is directed …

Cancer vaccine development Page 1 Schlom, Tsang, Kantor, Abrams, Zaremba, Greiner &
Hodge Cancer vaccine development Monthly Focus: Biologicals & Immunologicals Cancer …

Bluetongue virus (BTV) infection of ruminants is endemic throughout tropical and subtropical
regions of the world. However, the molecular epidemiology of BTV infection in China has not …

Antigenic variation is the means by which certain pathogenic microorganisms evade
immune surveillance. Through a variety of mechanisms, the antigenicity of their surface …

The field of peptide based cancer vaccines has evolved tremendously in the last decade of
this century. The exploration on how to apply the peptide knowledge for vaccination …