Crystallization is one of the important unit operations for the separation and purification of
solid products in the chemical, pharmaceutical, and pesticide industries, especially for …

Crystal measurement, especially on-line measurement, in industrial crystallization is always
a challenging topic in the past years, which is crucial to precisely understand crystal …

Precompetitive collaborations on new enabling technologies for research and development
are becoming popular among pharmaceutical companies. The Enabling Technologies …

Traditionally, off-line measurements via image analysis or laser diffraction methods are used
to analyze the crystal product. It is often beneficial to extract crystal samples intermittently …

This work focuses on an important problem that is the modeling and control of polymorphic
crystallization of indomethacin (IMC) in which one of the crystal forms consists of hair-like …

Due to the dynamic interactions of various crystallization phenomena, crystallization
processes are notoriously difficult to control. In some applications, supersaturation control is …

Innovations in the continuous crystallization field are required for the pharmaceutical
industry to go through the paradigm shift from batch to continuous processing. To do so …

The objective of the research was to improve the process design of a combined antisolvent–
cooling crystallization to reduce the degree of agglomeration of a real active pharmaceutical …

The concomitant polymorphism of the sulfur‐containing essential amino acid DL‐methionine
was revealed, and α‐and β‐polymorphic forms were separated from aqueous solution …

In this work, the polymorphic transformation of a dimorphic model compound, ortho-
aminobenzoic acid (OABA), is investigated using experimental characterization in …