From selenium to selenoproteins: synthesis, identity, and their role in human health

LV Papp, J Lu, A Holmgren… - Antioxidants & redox …, 2007 - liebertpub.com
The requirement of the trace element selenium for life and its beneficial role in human health
has been known for several decades. This is attributed to low molecular weight selenium …

[HTML][HTML] Selenium-binding protein 1 in human health and disease

M Elhodaky, AM Diamond - International journal of molecular sciences, 2018 - mdpi.com
Selenium-binding protein 1 (SBP1) is a highly conserved protein that covalently binds
selenium. SBP1 may play important roles in several fundamental physiological functions …

Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis

K Levanon, V Ng, HY Piao, Y Zhang, MC Chang… - Oncogene, 2010 - nature.com
Recent studies suggest that some serous ovarian carcinomas (SOCs) arise from the
fallopian tube (FT) epithelium rather than the ovarian surface epithelium. This hypothesis …

[HTML][HTML] A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism

Z Cai, JS Zhao, JJ Li, DN Peng, XY Wang… - Molecular & Cellular …, 2010 - ASBMB
Gastric cardia cancer (GCC), which occurs at the gastric-esophageal boundary, is one of the
most malignant tumors. Despite its high mortality and morbidity, the molecular mechanism of …

[HTML][HTML] Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines

S Mallett, A Timmer, W Sauerbrei… - British Journal of Cancer, 2010 - nature.com
Background: Poor reporting compromises the reliability and clinical value of prognostic
tumour marker studies. We review articles to assess the reporting of patients and events …

Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1α to promote hepatocellular carcinoma invasiveness

C Huang, G Ding, C Gu, J Zhou, M Kuang, Y Ji… - Clinical Cancer …, 2012 - AACR
Purpose: We aimed to characterize the role of selenium-binding protein 1 (SBP1) in
hepatocellular carcinoma (HCC) invasiveness and underlying clinical significance …

[HTML][HTML] Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure

SL Edassery, SV Shatavi, JP Kunkel, C Hauer… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To identify ovarian autoantigens associated with ovarian autoantibodies.
DESIGN: Hypothesis-generating prospective study. SETTING: Urban infertility referral …

Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein

W Fang, ML Goldberg, NM Pohl, X Bi, C Tong… - …, 2010 - academic.oup.com
Abstract Selenium-binding protein (SBP) 1 is present in reduced levels in several cancer
types as compared with normal tissues, and lower levels are associated with poor clinical …

[HTML][HTML] Reduced selenium-binding protein 1 in breast cancer correlates with poor survival and resistance to the anti-proliferative effects of selenium

S Zhang, F Li, M Younes, H Liu, C Chen, Q Yao - PloS one, 2013 - journals.plos.org
Supplemental dietary selenium is associated with reduced incidence of many cancers. The
antitumor function of selenium is thought to be mediated through selenium-binding protein 1 …

[HTML][HTML] Identification of novel biomarkers for sepsis prognosis via urinary proteomic analysis using iTRAQ labeling and 2D-LC-MS/MS

L Su, L Cao, R Zhou, Z Jiang, K Xiao, W Kong, H Wang… - PloS one, 2013 - journals.plos.org
Objectives Sepsis is the major cause of death for critically ill patients. Recent progress in
proteomics permits a thorough characterization of the mechanisms associated with critical …