Nicotine addiction: More than just dopamine

K Kim, MR Picciotto - Current Opinion in Neurobiology, 2023 - Elsevier
Despite decades of research and anti-tobacco messaging, nicotine addiction remains an
important public health problem leading to hundreds of thousands of deaths each year …

The rostromedial tegmental (RMTg)“brake” on dopamine and behavior: A decade of progress but also much unfinished work

TC Jhou - Neuropharmacology, 2021 - Elsevier
Between 2005 and 2009, several research groups identified a strikingly dense inhibitory
input to midbrain dopamine neurons arising from a previously uncharted region posterior to …

Is the antidepressant activity of selective serotonin reuptake inhibitors mediated by nicotinic acetylcholine receptors?

HR Arias, KM Targowska-Duda, J García-Colunga… - Molecules, 2021 - mdpi.com
It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce
antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating …

The co-use of nicotine and prescription psychostimulants: A review of their behavioral and neuropharmacological interactions

KR McNealy, L Weyrich, RA Bevins - Drug and Alcohol Dependence, 2023 - Elsevier
Background Nicotine is commonly co-used with other psychostimulants. These high co-use
rates have prompted much research on interactions between nicotine and psychostimulant …

Nicotine inhalant via E‐cigarette facilitates sensorimotor function recovery by upregulating neuronal BDNF–TrkB signalling in traumatic brain injury

D Wang, X Li, W Li, T Duong, H Wang… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Traumatic brain injury (TBI) causes lifelong physical and
psychological dysfunction in affected individuals. The current study investigated the effects …

Insulin decreases epileptiform activity in rat layer 5/6 prefrontal cortex in vitro

N Villalobos, E Ramírez‐Sánchez… - Synapse, 2023 - Wiley Online Library
Accumulating evidence indicates that insulin‐mediated signaling in the brain may play
important roles in regulating neuronal function. Alterations to insulin signaling are …

Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats

YS Chao, J Parrilla-Carrero, M Eid, OP Culver… - Cell Reports, 2023 - cell.com
Cocaine blocks dopamine reuptake, thereby producing rewarding effects that are widely
studied. However, cocaine also blocks serotonin uptake, which we show drives, in rats …

NMDA Receptor Activation and Ca2+/PKC Signaling in Nicotine-Induced GABA Transport Shift in Embryonic Chick Retina

AC Souto, MH Tempone, LAC Gonçalves… - Neurochemical …, 2023 - Springer
Nicotinic receptors are present in the retina of different vertebrates, and in the chick retina, it
is present during early development throughout to post-hatching. These receptors are …

[PDF][PDF] The co-use of nicotine and prescription psychostimulants: A comprehensive review of their behavioral and neuropharmacological interactions

KR McNealy, L Weyrich, RA Bevins - Authorea Preprints, 2023 - researchgate.net
Nicotine is commonly co-used with other psychostimulants. These high rates of co-use have
prompted much research on the interaction of nicotine and various psychostimulant drugs …

Opposing Effects of Nicotine on Hypothalamic Arcuate Nucleus Pomc and Npy Neurons

E Ramírez-Sánchez, A Mondragón-García… - Available at SSRN … - papers.ssrn.com
The hypothalamic arcuate nucleus of the hypothalamus (ARC) contains two main
populations of neurons essential for energy homeostasis: neuropeptide Y (NPY) neurons …