NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond
Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
Neutrophil extracellular traps and long COVID
A Shafqat, MH Omer, I Albalkhi… - Frontiers in …, 2023 - frontiersin.org
Post-acute COVID-19 sequelae, commonly known as long COVID, encompasses a range of
systemic symptoms experienced by a significant number of COVID-19 survivors. The …
systemic symptoms experienced by a significant number of COVID-19 survivors. The …
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
W Liang, Y Yang, S Gong, M Wei, Y Ma, R Feng… - Cell host & …, 2023 - cell.com
Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
(COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression …
Saracatinib, a selective src kinase inhibitor, blocks fibrotic responses in preclinical models of pulmonary fibrosis
F Ahangari, C Becker, DG Foster… - American Journal of …, 2022 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and often fatal
disorder. Two US Food and Drug Administration–approved antifibrotic drugs, nintedanib and …
disorder. Two US Food and Drug Administration–approved antifibrotic drugs, nintedanib and …
[HTML][HTML] The gut-lung axis in severe acute Pancreatitis-associated lung injury: The protection by the gut microbiota through short-chain fatty acids
Z Wang, J Liu, F Li, Y Luo, P Ge, Y Zhang… - Pharmacological …, 2022 - Elsevier
The role of gut microbiota in regulating the intestinal homeostasis, as well as the
pathogenesis of severe acute pancreatitis-associated lung injury (PALI) is widely …
pathogenesis of severe acute pancreatitis-associated lung injury (PALI) is widely …
Therapeutic targeting of intestinal fibrosis in Crohn's disease
Intestinal fibrosis is one of the most threatening complications of Crohn's disease. It occurs in
more than a third of patients with this condition, is associated with increased morbidity and …
more than a third of patients with this condition, is associated with increased morbidity and …
Neutrophil extracellular traps in airway diseases: Pathological roles and therapeutic implications
A Jo, DW Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are important effector cells of the innate immune response that fight pathogens
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …
Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27
DR Riehl, A Sharma, J Roewe… - Proceedings of the …, 2023 - National Acad Sciences
Externalized histones erupt from the nucleus as extracellular traps, are associated with
several acute and chronic lung disorders, but their implications in the molecular …
several acute and chronic lung disorders, but their implications in the molecular …
Macrophage and neutrophil interactions in the pancreatic tumor microenvironment drive the pathogenesis of pancreatic cancer
Simple Summary The survival rates for patients with pancreatic adenocarcinoma are very
low. This dismal prognosis is due in part to late detection and early development of …
low. This dismal prognosis is due in part to late detection and early development of …
METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung …
H Zhang, D Wu, Y Wang, K Guo… - Clinical and …, 2023 - Wiley Online Library
Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs),
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …