Glioblastoma (GBM) is the most aggressive and common form of primary brain cancer.
Several decades of research have provided great insight into GBM progression; however …

Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Despite promising preclinical results, average response rates to anti-VEGF therapies, such
as bevacizumab, are reduced for most cancers, while incurring in remarkable costs and side …

We synthesized new aroyl diheterocyclic pyrrole (ARDHEP) 15 that exhibited the hallmarks
of ferroptosis. Compound 15 strongly inhibited U-87 MG, OVCAR-3, and MCF-7 cancer cells …

Simple Summary As one of the most lethal human cancers, glioblastoma treatment is a real
challenge because of several resistance mechanisms, including limited drug entry into the …

Glioblastoma multiforme (GBM) is the most aggressive malignant tumor of the central
nervous system, with poor survival in both treated and untreated patients. Recent studies …

Background Single-cell RNA sequencing is the reference technique for characterizing the
heterogeneity of the tumor microenvironment. The composition of the various cell types …

Opinion statement Cranial radiation is ubiquitous in the treatment of primary malignant and
benign brain tumors as well as brain metastases. Improvement in radiotherapy targeting and …

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in
adults. Treatments include surgical resection, radiotherapy, and chemotherapy. Despite this …

Background and aim: Ever since the discovery of tumor-associated immune cells, there has
been growing interest in the understanding of the mechanisms underlying the crosstalk …