Global positioning system: understanding long noncoding RNAs through subcellular localization

J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …

Transport between the cell nucleus and the cytoplasm

D Görlich, U Kutay - Annual review of cell and developmental …, 1999 - annualreviews.org
▪ Abstract The compartmentation of eukaryotic cells requires all nuclear proteins to be
imported from the cytoplasm, whereas, for example, transfer RNAs, messenger RNAs, and …

The HIV-1 rev protein

VW Pollard, MH Malim - Annual review of microbiology, 1998 - annualreviews.org
▪ Abstract The nuclear export of intron-containing HIV-1 RNA is critically dependent on the
activity of Rev, a virally encoded sequence-specific RNA-binding protein. Rev shuttles …

Nucleocytoplasmic transport: signals, mechanisms and regulation

EA Nigg - Nature, 1997 - nature.com
In eukaryotic organisms, DNA replication and RNA biogenesis occur in the cell nucleus,
whereas protein synthesis occurs in the cytoplasm. Integration of these activities depends on …

HuR regulates p21 mRNA stabilization by UV light

W Wang, H Furneaux, H Cheng… - … and cellular biology, 2000 - Taylor & Francis
Expression of the cyclin-dependent kinase inhibitor p21 is highly induced by many stresses,
including exposure to short-wavelength UV light (UVC), which increases p21 mRNA …

[HTML][HTML] Transport of proteins and RNAs in and out of the nucleus

S Nakielny, G Dreyfuss - Cell, 1999 - cell.com
Eukaryotic cells are equipped with a machinery charged with the responsibility of
transporting a vast number of molecules in and out of the nucleus in a rapid, accurate, and …

[HTML][HTML] Yra1p, a conserved nuclear RNA‐binding protein, interacts directly with Mex67p and is required for mRNA export

K Sträßer, E Hurt - The EMBO journal, 2000 - embopress.org
Yra1p, a conserved nuclear RNA‐binding protein, interacts directly with Mex67p and is required
for mRNA export | The EMBO Journal All EMBO Press journals Open Access as of 1 January …

Identification of a tRNA-specific nuclear export receptor

U Kutay, G Lipowsky, E Izaurralde, FR Bischoff… - Molecular cell, 1998 - cell.com
In eukaryotes, tRNAs are synthesized in the nucleus and after several maturation steps
exported to the cytoplasm. Here, we identify exportin-t as a specific mediator of tRNA export …

[HTML][HTML] The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

WM Michael, PS Eder, G Dreyfuss - The EMBO journal, 1997 - embopress.org
Protein import into the nucleus and export from the nucleus are signal-mediated processes
that require energy. The nuclear transport process about which the most information is …

Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins

M Bui, EG Wills, A Helenius, GR Whittaker - Journal of virology, 2000 - Am Soc Microbiol
The protein kinase inhibitor H7 blocks influenza virus replication, inhibits production of the
matrix protein (M1), and leads to a retention of the viral ribonucleoproteins (vRNPs) in the …