Determinants of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction

MJ Haykowsky, CR Tomczak… - Journal of applied …, 2015 - journals.physiology.org
This mini-review summarizes the literature regarding the mechanisms of exercise
intolerance in patients with heart failure and reduced or preserved ejection fraction (HFREF …

Frailty and multiple comorbidities in the elderly patient with heart failure: implications for management

K Murad, DW Kitzman - Heart failure reviews, 2012 - Springer
Heart failure (HF) in the elderly is a major public health problem, and its prevalence is rising.
Outcomes of HF in the elderly have not changed in the past 2 decades despite the …

Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction

S Ather, W Chan, B Bozkurt, D Aguilar… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to evaluate the prevalence and prognostic impacts of
noncardiac comorbidities in patients with heart failure (HF) with preserved ejection fraction …

Knowledge gaps in cardiovascular care of the older adult population: a scientific statement from the American Heart Association, American College of Cardiology, and …

MW Rich, DA Chyun, AH Skolnick, KP Alexander… - Circulation, 2016 - Am Heart Assoc
The incidence and prevalence of most cardiovascular disorders increase with age, and
cardiovascular disease is the leading cause of death and major disability in adults≥ 75 …

Methods of data collection and definitions of cardiac outcomes in the Rotterdam Study

MJG Leening, M Kavousi, J Heeringa… - European journal of …, 2012 - Springer
The prevalence of cardiovascular diseases is rising. Therefore, adequate risk prediction and
identification of its determinants is increasingly important. The Rotterdam Study is a …

Exercise training as therapy for heart failure: current status and future directions

JL Fleg, LS Cooper, BA Borlaug… - Circulation: Heart …, 2015 - Am Heart Assoc
Background Despite a variety of pharmacological and device therapies for persons with
chronic heart failure (HF), prognosis and quality of life (QOL) remain poor. The need for new …

Heart failure with preserved ejection fraction: persistent diagnosis, therapeutic enigma

T Bhuiyan, MS Maurer - Current cardiovascular risk reports, 2011 - Springer
Heart failure with preserved ejection fraction (HFPEF) is increasing in prevalence with the
aging of the population, and morbidity and mortality rates are comparable to that of heart …

Exclusion of elderly people from randomized clinical trials of drugs for ischemic heart disease

FT Bourgeois, L Orenstein, S Ballakur… - Journal of the …, 2017 - Wiley Online Library
Objectives To measure exclusion of elderly adults from randomized trials studying drug
interventions for ischemic heart disease (IHD) and describe the characteristics of these trials …

Contemporary prevalence and correlates of incident heart failure with preserved ejection fraction

JH Gurwitz, DJ Magid, DH Smith, RJ Goldberg… - The American journal of …, 2013 - Elsevier
BACKGROUND: We assessed the prevalence of preserved left ventricular ejection fraction
in patients with incident heart failure and differences in the demographic and clinical …

Knowledge gaps in cardiovascular care of older adults: a scientific statement from the American Heart Association, American College of Cardiology, and American …

MW Rich, DA Chyun, AH Skolnick… - Journal of the …, 2016 - Wiley Online Library
The incidence and prevalence of most cardiovascular disorders increase with age, and
cardiovascular disease (CVD) is the leading cause of death and major disability in adults …