Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention

SS Hecht, DK Hatsukami - Nature Reviews Cancer, 2022 - nature.com
Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …

Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer

AW Caliri, S Tommasi, A Besaratinia - Mutation Research/Reviews in …, 2021 - Elsevier
Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer

DC Bruhm, D Mathios, ZH Foda, AV Annapragada… - Nature …, 2023 - nature.com
Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive
diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in …

Mutational signatures associated with tobacco smoking in human cancer

LB Alexandrov, YS Ju, K Haase, P Van Loo… - Science, 2016 - science.org
Tobacco smoking increases the risk of at least 17 classes of human cancer. We analyzed
somatic mutations and DNA methylation in 5243 cancers of types for which tobacco smoking …

Fanconi anaemia and cancer: an intricate relationship

G Nalepa, DW Clapp - Nature Reviews Cancer, 2018 - nature.com
Fanconi anaemia (FA) is a genetic disorder that is characterized by bone marrow failure
(BMF), developmental abnormalities and predisposition to cancer. Together with other …

DNA damage and associated DNA repair defects in disease and premature aging

V Tiwari, DM Wilson - The American Journal of Human Genetics, 2019 - cell.com
Genetic information is constantly being attacked by intrinsic and extrinsic damaging agents,
such as reactive oxygen species, atmospheric radiation, environmental chemicals, and …

[PDF][PDF] Smoking and male infertility: an evidence-based review

A Harlev, A Agarwal, SO Gunes… - The world journal of …, 2015 - synapse.koreamed.org
Many studies have reported that the contents of cigarette smoke negatively affect sperm
parameters, seminal plasma, and various other fertility factors. Nevertheless, the actual …

E-cigarettes and smoking cessation: evidence from a systematic review and meta-analysis

MA Rahman, N Hann, A Wilson, G Mnatzaganian… - PloS one, 2015 - journals.plos.org
Background E-cigarettes are currently being debated regarding their possible role in
smoking cessation and as they are becoming increasingly popular, the research to date …

[HTML][HTML] Tailored carbon materials (TCM) for enhancing photocatalytic degradation of polyaromatic hydrocarbons

A Singh, J Dhau, R Kumar, R Badru, P Singh… - Progress in Materials …, 2024 - Elsevier
This comprehensive review explores the potential of tailored carbon materials (TCM) for
efficient photocatalytic degradation of polyaromatic hydrocarbons (PAHs), which are …

Vaping dose, device type, and e-liquid flavor are determinants of DNA damage in electronic cigarette users

S Tommasi, H Blumenfeld… - Nicotine and Tobacco …, 2023 - academic.oup.com
Introduction Despite the widespread use of electronic cigarettes, the long-term health
consequences of vaping are largely unknown. Aims and Methods We investigated the DNA …