An update on diagnostic and prognostic biomarkers for traumatic brain injury
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …
[HTML][HTML] Traumatic brain injury and Alzheimer's disease: the cerebrovascular link
J Ramos-Cejudo, T Wisniewski, C Marmar… - …, 2018 - thelancet.com
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …
disorders, whose complex relationship is not completely understood. Cerebrovascular …
[HTML][HTML] Optical imaging and spectroscopy for the study of the human brain: status report
This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …
extensive and diverse toolkit of novel methods to explore brain health and function. While …
Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …
important information about vascular health in a range of brain conditions and diseases …
Pathophysiology of traumatic brain injury
KJ Dixon - Physical Medicine and Rehabilitation Clinics, 2017 - pmr.theclinics.com
Traumatic brain injury (TBI) may have many different causes, including a blow to the head,
penetration of the skull, fast acceleration or deceleration of the head, or exposure to a blast …
penetration of the skull, fast acceleration or deceleration of the head, or exposure to a blast …
Response of the cerebral vasculature following traumatic brain injury
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model
CA Tagge, AM Fisher, OV Minaeva… - Brain, 2018 - academic.oup.com
The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …
encephalopathy, and the relationships between these disorders, are poorly understood. We …
Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature
Cerebrovascular injury (CVI) is a common pathology caused by infections, injury, stroke,
neurodegeneration and autoimmune disease. Rapid resolution of a CVI requires a …
neurodegeneration and autoimmune disease. Rapid resolution of a CVI requires a …
A framework to advance biomarker development in the diagnosis, outcome prediction, and treatment of traumatic brain injury
EA Wilde, IB Wanner, K Kenney, J Gill… - Journal of …, 2022 - liebertpub.com
Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
Traumatic microbleeds suggest vascular injury and predict disability in traumatic brain injury
Traumatic microbleeds are small foci of hypointensity seen on T2*-weighted MRI in patients
following head trauma that have previously been considered a marker of axonal injury. The …
following head trauma that have previously been considered a marker of axonal injury. The …