The development of drug addiction is associated with functional adaptations within the
reward circuitry, within which the nucleus accumbens (NAc) is anatomically positioned as an …

Drug addiction is a devastating disorder with a huge economic and social burden for
modern society. Although an individual may slip into drug abuse throughout his/her life …

Background Disruptions in the decision-making processes that guide action selection are a
core feature of many psychiatric disorders, including addiction. Decision making is …

Background Drug-induced alterations to the dopamine system in stimulant use disorder
(SUD) are hypothesized to impair reinforcement learning (RL). Computational modeling …

Incubation of food craving is an abstinence‐dependent increase in responding for reward‐
paired cues. Incubation of craving was first reported for rats responding for cocaine‐paired …

The insula contributes to behavioral control and is disrupted by substance abuse, yet we
know little about the neural signals underlying these functions or how they are disrupted …

There is no single way to represent a task. Indeed, despite experiencing the same task
events and contingencies, different subjects may form distinct task representations. As …

Although impulsive action is strongly associated with addiction, the neural underpinnings of
this relationship and how they are influenced by sex have not been well characterized. Here …

Addiction is a disorder of behavioral control and learning. While this may reflect pre-existing
propensities, drug use also clearly contributes by causing changes in outcome processing in …

Substance use disorder is a major concern, with few therapeutic options. Heparan sulfate
(HS) and chondroitin sulfate (CS) interact with a plethora of growth factors and their …