The development of drug addiction is associated with functional adaptations within the
reward circuitry, within which the nucleus accumbens (NAc) is anatomically positioned as an …

Drug addiction is a devastating disorder with a huge economic and social burden for
modern society. Although an individual may slip into drug abuse throughout his/her life …

Background Disruptions in the decision-making processes that guide action selection are a
core feature of many psychiatric disorders, including addiction. Decision making is …

Background Drug-induced alterations to the dopamine system in stimulant use disorder
(SUD) are hypothesized to impair reinforcement learning (RL). Computational modeling …

The insula contributes to behavioral control and is disrupted by substance abuse, yet we
know little about the neural signals underlying these functions or how they are disrupted …

Incubation of food craving is an abstinence‐dependent increase in responding for reward‐
paired cues. Incubation of craving was first reported for rats responding for cocaine‐paired …

In 2014, we participated in a special issue of Frontiers examining the neural processing of
appetitive and aversive events. Specifically, we reviewed brain areas that contribute to the …

Addiction has long been characterized by diminished executive function, control, and
impulsivity management. In particular, these deficits often manifest themselves as …

Addiction is a disorder of behavioral control and learning. While this may reflect pre-existing
propensities, drug use also clearly contributes by causing changes in outcome processing in …

Although maladaptive decision-making is a defining feature of drug abuse and addiction, we
have yet to ascertain how cocaine self-administration disrupts neural signals in anterior …