A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction …

Substance use disorder is a major concern, with few therapeutic options. Heparan sulfate
(HS) and chondroitin sulfate (CS) interact with a plethora of growth factors and their …

Although impulsive action is strongly associated with addiction, the neural underpinnings of
this relationship and how they are influenced by sex have not been well characterized. Here …

There is no single way to represent a task. Indeed, despite experiencing the same task
events and contingencies, different subjects may form distinct task representations. As …

Previous exposure to drugs of abuse produces impairments in studies of reversal learning,
delay discounting and response inhibition tasks. While these studies contribute to the …

Background: Impulsivity is a complex multi-dimensional combination of behaviors which
include: ineffective impulse control, premature decision-making and inability to delay …

The insula has become a significant brain region in the study of both normal and impaired
behavior and decision-making and has emerged as an important contributor to drug …

Accumulating evidence in the past decade implicates histone-modifying enzymes, such as
class I histone deacetylases (HDACs), in learning and memory and, recently, habit …

Excessive use of cocaine is known to induce changes in brain white and gray matter. It is
unknown whether the extent of these changes is related to individual differences in …

Pharmacology has risen to a new horizon with its many branches of clinical research and
practices. One among these is the field of neuro-psycho-pharmacology. Neuroscience is the …