Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS). Although emerging evidence has shown that changes in …

Multiple sclerosis (MS) is an incurable and progressive neurodegenerative disease that
affects more than 2.5 million people worldwide and brings tremendous economic pressures …

Pain is one of the most common symptoms experienced by patients. The use of current
analgesics is limited by low efficacy and important side effects. Transient receptor potential …

Abstract Background Antipsychotic medications (APMs) and selective serotonin reuptake
inhibitors (SSRIs) are frequently utilized in patients with neuroinflammatory disorders, such …

Multiple sclerosis is an autoimmune disease characterised by demyelination in the central
nervous system. The cuprizone-induced demyelination model is often used in mice to test …

Neuropathy is one of the most frequent and continuously growing complications of diabetes.
Due to the multitude of mechanisms involved in the pathogenesis of diabetic neuropathy …

Transient Receptor Potential Ankyrin 1 (TRPA1) is a non-selective cation channel involved
in sensitivity to a plethora of irritating agents and endogenous mediators of oxidative stress …

The current research aimed to examine the ameliorative role of febuxostat (FEB), a highly
potent xanthine oxidase inhibitor, against 5-fluorouracil (5-FU)-induced parotid salivary …

Background and objectives: Worldwide, approximately 500 million people suffer from
diabetes and at least 50% of these people develop neuropathy. Currently, therapeutic …

(1) Background: Globally, about 600 million people are afflicted with diabetes, and one of its
most prevalent complications is neuropathy, a debilitating condition. At the present time, the …