Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of
which have been only partially elucidated. The hippocampus serves as a major target of …

Stress exposure is one of the greatest risk factors for psychiatric illnesses, including major
depressive disorder (MDD) and posttraumatic stress disorder (PTSD). Enhancing stress …

Studies in humans and rodents suggest a critical role for the hippocampal formation in
cognition and emotion, but also in the adaptation to stressful events. Successful stress …

Exposure to stress is recognized to be a triggering factor in several mood disorders,
including depression and anxiety. There is very little understanding of why female subjects …

Fear generalization is a conserved survival mechanism that can become maladaptive in the
face of traumatic situations, a feature central to certain anxiety disorders including …

Ketamine has been reported to exert a prophylactic effect against stress-induced depressive-
like behavior by modulating the guanosine-based purinergic system. However, the …

Depression is a neuropsychiatric disorder with a high impact on the worldwide population.
To overcome depression, antidepressant drugs are the first line of treatment. However, pre …

Neural proliferation in the dentate gyrus (DG) is closely linked with learning and memory, but
the transcriptional programming that drives adult proliferation remains incompletely …

Neuroinflammation is often associated with the development of depressive and anxiety
disorders. The hippocampus is one of the brain regions affected by inflammation that is …

Neuron‐restrictive silencing factor (NRSF) is a zinc‐finger transcription factor that regulates
expression of a diverse set of genes. However, NRSF function in brain development still …