Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice

O Skiteva, N Yao, I Mantas, X Zhang… - npj Parkinson's …, 2023 - nature.com
In Parkinson's disease (PD), axons of dopaminergic (DA) neurons in the substantia nigra
pars compacta (SNc) degenerate before their cell bodies. Calcium influx during pacemaker …

Impact of micronutrients and nutraceuticals on cognitive function and performance in Alzheimer's disease

L Guarnieri, F Bosco, A Leo, R Citraro, E Palma… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a major global health problem today and is the most common
form of dementia. AD is characterized by the formation of β-amyloid (Aβ) plaques and …

A Review on Bioactive Compounds, Ethnomedicinal Importance and Pharmacological Activities of Talinum triangulare (Jacq.) Willd

A Dinesh, A Kumar - Chemistry & Biodiversity, 2023 - Wiley Online Library
Abstract Talinum triangulare (Jacq.) Willd. is a traditional leafy vegetable used by tribal
communities for ethnomedicinal and ethnoculinary preparations. This article reviews the …

Integrated blood and organ profile analysis to evaluate ameliorative effects of kaempferol on 5-fluorouracil-induced toxicity

A Sharma, MR Chorawala, RM Rawal… - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) treatment strategies encompass a triad of medical interventions:
surgery, radiotherapy, and chemotherapy. Among these, the use of chemotherapy …

Waste to wealth: microbial-based valorization of grape pomace for nutraceutical, cosmetic, and therapeutic applications to promote circular economy

GK Sodhi, G Kaur, N George, HK Walia, D Sillu… - Process Safety and …, 2024 - Elsevier
Grape pomace, the solid residue produced during fruit extraction, is a significant by-product
of the wine industry. The industry generates vast amounts of grape pomace each year …

Metabolic profiling of Chimonanthus grammatus via UHPLC-HRMS-MS with computer-assisted structure elucidation and its antimicrobial activity

H Hu, V Tekin, B Hu, M Yaghoobi, A Khan… - Frontiers in Plant …, 2023 - frontiersin.org
Chimonanthus grammatus is used as Hakka traditional herb to treat cold, flu, etc. So far, the
phytochemistry and antimicrobial compounds have not been well investigated. In this study …

Structural characterization and stability of glycated bovine serum albumin-kaempferol nanocomplexes

RH Ma, W Wang, CP Hou, YF Man, ZJ Ni, K Thakur… - Food Chemistry, 2023 - Elsevier
Kaempferol (Kae), a flavonoid is endowed with various functions. However, due to its poor
water solubility and stability, its application in the food and pharmaceutical fields remains …

Overexpression of MrMYB12 or MrMYB12/MrF3'5'H results in flavonol-rich tomato fruit that improves resistance against Botrytis cinerea during the shelf life period

Y Cao, R Zhang, R Ou, Y Mei, X Cui, T Zhang… - Postharvest Biology and …, 2024 - Elsevier
Flavonols are one class of flavonoids that play a crucial role in regulating plant growth and
promoting stress resistance. They are also important dietary components in horticultural …

Kaempferol attenuates particle-induced osteogenic impairment by regulating ER stress via the IRE1α–XBP1s pathway

X Yu, Z Ren, Y Wang, G Yuan, J Hu, L Song… - Journal of Biological …, 2024 - ASBMB
Periprosthetic osteolysis and subsequent aseptic loosening are the primary causes of failure
following total joint arthroplasty. Wear particle–induced osteogenic impairment is recognized …

[HTML][HTML] Genome-wide identification and characterization of flavonol synthase (FLS) gene family in Brassica vegetables and their roles in response to biotic and abiotic …

L Yue, M Zhong, D Kang, H Qin, H Li, X Chai… - Scientia …, 2024 - Elsevier
Flavonol synthase (FLS) serves as a pivotal enzyme in the flavonol biosynthesis pathway,
contributing to the abundance of flavonol compounds found in Brassica vegetables …