Drug development, Brazilian biodiversity and political choices: Where are we heading?

PMP Ferreira, DDR Arcanjo… - Journal of Toxicology and …, 2023 - Taylor & Francis
The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural product reports, 2008 - pubs.rsc.org
Covering: July 2005 to June 2006. Previous review: Nat. Prod. Rep., 2007, 24, 223–246 This
review covers the isolation, structure determination, synthesis and biological activity of …

[图书][B] Hayes' principles and methods of toxicology

AW Hayes, T Kobets - 2023 - books.google.com
Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Phylogenetic systematics of dart-poison frogs and their relatives (Amphibia: Athesphatanura: Dendrobatidae)

T Grant, DR Frost, JP Caldwell, RON Gagliardo… - Bulletin of the American …, 2006 - BioOne
The known diversity of dart-poison frog species has grown from 70 in the 1960s to 247 at
present, with no sign that the discovery of new species will wane in the foreseeable future …

A review of chemical ecology in poison frogs

RA Saporito, MA Donnelly, TF Spande, HM Garraffo - Chemoecology, 2012 - Springer
Herein we review what is known about the chemical ecology of poison frogs with a focus on
dendrobatid poison frogs. While five anuran families are known to have an alkaloid-derived …

Characterization of imine reductases in reductive amination for the exploration of structure-activity relationships

SL Montgomery, A Pushpanath, RS Heath… - Science …, 2020 - science.org
Imine reductases (IREDs) have shown great potential as catalysts for the asymmetric
synthesis of industrially relevant chiral amines, but a limited understanding of sequence …

Diet of Epipedobates flavopictus (Anura: Dendrobatidae) in a neotropical savanna

GM Biavati, HC Wiederhecker, GR Colli - Journal of herpetology, 2004 - BioOne
A central issue in comparative biology is identifying the relative importance of historical
(phylogenetic) versus present-day (ecological) factors in shaping phenotypic traits of …

Quinoline, quinazoline and acridone alkaloids

JP Michael - Natural Product Reports, 2005 - pubs.rsc.org
Covering: July 2003 to June 2004. Previous review: Nat. Prod. Rep., 2004, 21, 650. This
review covers the isolation, structure determination, synthesis and biological activity of …

Simple indolizidine and quinolizidine alkaloids

JP Michael - The alkaloids: Chemistry and biology, 2016 - Elsevier
This review of simple indolizidine and quinolizidine alkaloids (ie, those in which the parent
bicyclic systems are in general not embedded in polycyclic arrays) is an update of the …

Geographic and Seasonal Variation in Alkaloid-Based Chemical Defenses of Dendrobates pumilio from Bocas del Toro, Panama

RA Saporito, MA Donnelly, HM Garraffo… - Journal of chemical …, 2006 - Springer
Poison frogs contain an alkaloid-based chemical defense that is derived from a diet of
certain alkaloid-containing arthropods, which include mites, ants, beetles, and millipedes …