miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
Non-coding RNA-based therapeutics in cancer therapy: An emphasis on Wnt/β-catenin control
A Taheriazam, SD Bayanzadeh, MH Farahani… - European Journal of …, 2023 - Elsevier
Non-coding RNA transcripts are RNA molecules that have mainly regulatory functions and
they do not encode proteins. microRNAs (miRNAs), lncRNAs and circRNAs are major types …
they do not encode proteins. microRNAs (miRNAs), lncRNAs and circRNAs are major types …
[HTML][HTML] Role and Dysregulation of miRNA in Patients with Parkinson's Disease
M Salemi, G Marchese, G Lanza, FII Cosentino… - International Journal of …, 2022 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative synucleinopathy that has a not yet fully
understood molecular pathomechanism behind it. The role of risk genes regulated by small …
understood molecular pathomechanism behind it. The role of risk genes regulated by small …
[HTML][HTML] Protective role of circRNA CCND1 in ulcerative colitis via miR-142-5p/NCOA3 axis
P Xiang, T Ge, J Zhou, Y Zhang - BMC gastroenterology, 2023 - Springer
Background Increasing research indicates that circular RNAs (circRNAs) play critical roles in
the development of ulcerative colitis (UC). This study aimed to determine the role of circRNA …
the development of ulcerative colitis (UC). This study aimed to determine the role of circRNA …
Exosomal miRNAs assist in the crosstalk between tumor cells and immune cells and its potential therapeutics
X Chen, Y Li, M Li, Y Xie, K Wang, L Zhang, Z Zou… - Life Sciences, 2023 - Elsevier
Exosomes are small extracellular vesicles that carry active substances (including proteins,
lipids, and nucleic acids) and are essential for homeostasis and signal transmission. Recent …
lipids, and nucleic acids) and are essential for homeostasis and signal transmission. Recent …
[HTML][HTML] Interaction of cervical microbiome with epigenome of epithelial cells: Significance of inflammation to primary healthcare
V Holubekova, Z Kolkova, I Kasubova… - Biomolecular …, 2022 - degruyter.com
One pillar of the predictive, preventive, and personalized medicine framework strategies is
the female health. The evaluation of women's lifestyle and dietary habits in context with …
the female health. The evaluation of women's lifestyle and dietary habits in context with …
miR‐142‐3p/5p role in cancer: From epigenetic regulation to immunomodulation
MicroRNAs (miRNAs) play critical roles in cancer pathobiology, acting as regulators of gene
expression and pivotal drivers of tumorigenesis. It is believed that miRNAs act through …
expression and pivotal drivers of tumorigenesis. It is believed that miRNAs act through …
Th17 cells target the metabolic miR‐142‐5p–succinate dehydrogenase subunit C/D (SDHC/SDHD) axis, promoting invasiveness and progression of cervical cancers
M Pohlers, S Gies, T Taenzer, R Stroeder… - Molecular …, 2023 - Wiley Online Library
During cervical carcinogenesis, T‐helper (Th)‐17 cells accumulate in the peripheral blood
and tumor tissues of cancer patients. We previously demonstrated that Th17 cells are …
and tumor tissues of cancer patients. We previously demonstrated that Th17 cells are …
A novel frameshift variant of LMX1A that leads to autosomal dominant non-syndromic sensorineural hearing loss: functional characterization of the C-terminal domain …
M Xiao, Y Zheng, KH Huang, S Yu… - Human Molecular …, 2023 - academic.oup.com
Non-syndromic sensorineural hearing loss (NSHL) is a group of genetically heterogeneous
conditions with broad phenotypic heterogeneity. There is, at present, no curative treatment …
conditions with broad phenotypic heterogeneity. There is, at present, no curative treatment …
[HTML][HTML] Novel_circ_003686 regulates the osteogenic differentiation of MSCs in patients with myeloma bone disease through miR-142-5p/IGF1 axis
L Qiu, L Ma, D Chen, N Zhang, J Cai, Q Zhang… - Journal of Bone …, 2023 - Elsevier
Objectives Circ_003686 is a novel_circRNA with abnormally low expression found in the
samples of multiple myeloma bone disease (MBD) patients. The current research intended …
samples of multiple myeloma bone disease (MBD) patients. The current research intended …