Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Chronic inflammation is a highly prevalent consequence of changes in environmental and
lifestyle factors that contribute to the development of cancer. The basis for this critical …

Organoid culture has been extensively exploited for normal tissue reconstruction and
disease modeling. However, it is still challenging to establish organoids that mimic in vivo …

Yak milk is a characteristic animal product of yaks in the Qinghai-Tibet Plateau. Although yak
milk production is low, it is richer in nutrients such as protein, fat, and lactose, a more …

Mammary gland development occurs mainly after birth and is composed of three successive
stages: puberty, pregnancy and lactation, and involution. These developmental stages are …

Vitamin A (all-trans-retinol), its active derivatives retinal and retinoic acid, and their synthetic
analogues constitute the group of retinoids. It is obtained from diet either as preformed …

The stromal microenvironment regulates mammary gland development and tumorigenesis.
In normal mammary glands, the stromal microenvironment encompasses the ducts and …

Amino acids can activate mTOR to promote milk synthesis in mammary epithelial cells
(MECs), but the underlying molecular mechanism is still largely unknown. The objective is to …

White adipocytes in the mammary gland stroma comprise the majority of the mammary gland
mass. White adipocytes regulate numerous hormonal and metabolic processes and exhibit …

In this review we have showcased the preclinical development of original amphiphilic
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …