In the 30 years since the first report of parental imprinting in insulin-like growth factor 2 (Igf2)
knockout mouse models, we have learnt much about the structure of this protein, its role and …

Beckwith-Wiedemann syndrome (BWS) is a clinically and genetically heterogeneous
overgrowth disease. BWS is caused by (epi) genetic defects at the 11p15 chromosomal …

Background There is widespread interest in the three-dimensional chromatin conformation
of the genome and its impact on gene expression. However, these studies frequently do not …

Different classes of non-coding RNA (ncRNA) influence the organization of chromatin.
Imprinted gene domains constitute a paradigm for exploring functional long ncRNAs …

Large/abnormal offspring syndrome (LOS/AOS) is a congenital overgrowth syndrome
reported in ruminants produced by assisted reproduction (ART-LOS) which exhibit global …

DNA methylation, chromatin-binding proteins, and DNA looping are common components
regulating genomic imprinting which leads to parent-specific monoallelic gene expression …

Genomic and transcriptomic image data, represented by DNA and RNA fluorescence in situ
hybridization (FISH), respectively, together with proteomic data, particularly that related to …

The placental methylation pattern is crucial for the regulation of genes involved in
trophoblast invasion and placental development, both key events for fetal growth. We …

Management of hepatoblastoma (HB), the most frequent pediatric liver cancer, is based on
surgical resection and perioperative chemotherapy regimens. In this study, we aimed to …

Beckwith–Wiedemann Syndrome (BWS) is an imprinting disorder characterized by
overgrowth, stemming from various genetic and epigenetic changes. This study delves into …