Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Emerging research has revealed regulation of colorectal cancer metabolism by bacteria.
Fusobacterium nucleatum (Fn) plays a crucial role in the development of colorectal cancer …

Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

Colorectal cancer (CRC) is the third most frequent malignant tumor. The gut microbiome acts
as a vital component of CRC etiology. Fusobacterium nucleatum (Fn) is a key member of …

Evidence shows that the enzyme human cytochrome P450 1A1 (CYP1A1) is associated with
cancer; indeed, it is shown to play a key role in the occurrence of many cancers. Therefore …

Redox stress is a common feature of gut disorders such as colonic inflammation
(inflammatory bowel disease or IBD) and colorectal cancer (CRC). This leads to increased …

Arsenic is well-recognized as one of the most hazardous elements which is characterized by
its omnipresence throughout the environment in various chemical forms. From the simple …

Esophageal squamous cell carcinoma (ESCC) is one of the most common aggressive
malignancies worldwide, particularly in northern China. The absence of specific early …

Oxidative stress is emerging as an important contributor to the pathogenesis of colorectal
cancer (CRC), however, the molecular mechanisms by which the disturbed redox balance …