Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

Clinicians have long sought to characterize biological markers of neoplasia as objective
indicators of tumor presence, pathogenicity, and prognosis. Armed with data that correlate …

Purpose: To determine whether the selective BRAF inhibitor, dabrafenib, can stimulate
radioiodine uptake in BRAF V600E-mutated unresectable or metastatic iodine-refractory …

Background: There is conflicting literature regarding the association of the BRAF V600E
mutation and aggressive clinicopathological features of papillary thyroid cancer (PTC) …

Objective Transcriptional activating mutations in the promoter of the telomerase reverse
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …

BRAF, a cytoplasmic serine–threonine protein kinase, plays a critical role in cell signaling as
an activator within the mitogen-activated protein kinase (MAPK) pathway. The most common …

近年来, 甲状腺癌在全球的发病率呈明显上升趋势, 成为备受关注的恶性肿瘤之一.
虽然甲状腺癌的发病机制及其影响因素目前尚不十分明确, 但经过多年临床实验研究及流行病学 …

Papillary thyroid cancer (PTC) offers excellent prognosis, however relapse risk or persistent
disease is related to~ 30%. Currently, attention is paid to the possibility of patient group …

Papillary thyroid cancer (PTC) is the most common tumor subtype of thyroid cancer.
However, not all PTCs are responsive to current surgical and radioiodine treatment. The well …

Apigenin, abundantly present in fruits and vegetables, is recognized as a flavonoid with anti-
inflammatory, antioxidant and anticancer properties. In this study, we first investigated the …