Analysis of BRAFV600E mutation and DNA methylation improves the diagnostics of thyroid fine needle aspiration biopsies

B Zhang, S Liu, Z Zhang, J Wei, Y Qu, K Wu, Q Yang… - Diagnostic …, 2014 - Springer
Background Thyroid nodules with indeterminate cytological features on fine needle
aspiration biopsy specimens (FNABs) have a~ 20% risk of thyroid cancer. BRAF V600E …

Molecular signatures of a disturbed nasal barrier function in the primary tissue of Wegener's granulomatosis

M Laudien, R Häsler, J Wohlers, J Böck… - Mucosal …, 2011 - nature.com
Wegener's granulomatosis (WG) is a complex autoimmune disease of unknown etiology,
frequently involving localized inflammation of the nasal mucosa as an early manifestation …

The urokinase plasminogen activating system in thyroid cancer: clinical implications

E Baldini, S Sorrenti, E D'ARMIENTO… - Il Giornale di …, 2012 - journals.lww.com
The urokinase plasminogen activator (uPA) system (uPAS) comprises the uPA, its cell
membrane receptor (uPAR) and two specific inhibitors, the plasminogen activator inhibitor 1 …

Not the same thing: metastatic PTCs have a different background than ATCs

D de Biase, F Torricelli, M Ragazzi… - Endocrine …, 2018 - ec.bioscientifica.com
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive form of thyroid cancer. By
contrast, differentiated papillary thyroid cancer (PTC) only rarely behave aggressively and …

Analysis of biomarkers and association with clinical outcomes in patients with differentiated thyroid cancer: Subanalysis of the sorafenib phase III DECISION trial

MS Brose, M Schlumbeger, M Jeffers, C Kappeler… - Clinical Cancer …, 2019 - AACR
Abstract Purpose: The phase III DECISION trial (NCT00984282; EudraCT: 2009-012007-25)
established sorafenib efficacy in locally recurrent or metastatic, progressive, differentiated …

Hyperparathyroid genes: sequences reveal answers and questions

SJ Marx - Endocrine Practice, 2011 - Elsevier
Objective: To review hyperparathyroid syndromes and genes. Methods: Pertinent original
studies from the literature are discussed. Results: Six main hyperparathyroid syndromes are …

Laser capture microdissection is a valuable tool in the preoperative molecular screening of follicular lesions of the thyroid: an institutional experience

M Bongiovanni, F Molinari, M Eszlinger… - …, 2015 - Wiley Online Library
Objectives The application of molecular tests to thyroid fine needle aspiration (FNA) has
been shown to be a valuable tool to better refine the pre‐operative malignant risk of patients …

Gene expression profiles for radiation-induced thyroid cancer

C Maenhaut, V Detours, G Dom, D Handkiewicz-Junak… - Clinical oncology, 2011 - Elsevier
The question whether radiation-induced thyroid cancer differs by its molecular biology from
sporadic disease still remains. Studies on tissue from patients who developed thyroid cancer …

Comparison of histopathological features and prognosis of classical and follicular variant papillary thyroid carcinoma

F Tunca, IC Sormaz, Y Iscan, YG Senyurek… - Journal of …, 2015 - Springer
Purpose To compare the histopathological features and the outcomes of the follicular variant
and classical variant of papillary thyroid carcinoma. Material and the methods Demographic …

Molecular diagnostics of fine needle aspiration for the presurgical screening of thyroid nodules

P Fallahi, R Giannini, P Miccoli, A Antonelli… - Current …, 2014 - ingentaconnect.com
“The incidence of thyroid cancer, the most common endocrine malignancy, is rising. The two
most common types of thyroid cancer are papillary and follicular” thyroid carcinomas.“Fine …