Complex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse model

DW Kim, RL Walker, PS Meltzer, S Cheng - Carcinogenesis, 2013 - academic.oup.com
Despite recent advances, understanding of molecular genetic alterations underlying thyroid
carcinogenesis remains unclear. One key question is how dynamic temporal changes in …

Application of molecular diagnostics to the evaluation of the surgical approach to thyroid cancer

P Miccoli - Current genomics, 2014 - ingentaconnect.com
Recent important studies that include long-term follow-up have shown that BRAF and RAS
mutations can have negative implications for disease recurrence and survival. BRAF …

[PDF][PDF] Selective inhibitors of aurora kinases inhibit proliferation, reduce cell viability and impair cell cycle progression in papillary thyroid carcinoma cells

E Baldini, C Tuccilli, N Prinzi, S Sorrenti… - J Biol Regul Homeost …, 2015 - researchgate.net
794 E. BALDINI ET AL. progressive disease. Among these, sorafenib and lenvatinib
mesylate have been recently approved by the Food and Drug Administration for the …

[PDF][PDF] 毒理基因组学研究进展

陆韻, 侯凌燕, 胡洪营, 李莉 - 2010 - jeesci.com
毒理基因组学是利用最新的基因组学技术来进行毒理学研究的新兴学科. 它能够快速全面地检测
出化合物和生物体相互作用后的全基因组表达的变化, 再通过生物信息学的方法对化合物的毒性 …

The pituitary tumor transforming gene in thyroid cancer

GD Lewy, N Sharma, RI Seed, VE Smith… - Journal of …, 2012 - Springer
The pituitary tumor transforming gene (PTTG) is a multifunctional proto-oncogene that is
over-expressed in various tumors including thyroid carcinomas, where it is a prognostic …

[引用][C] 甲状腺乳头状癌中TSHR 基因启动子区5'-CpG 岛甲基化研究

许敬, 葛明华, 凌志强, 程蕾, 徐加杰 - 肿瘤, 2010

Expression of Notch 1 receptor associated with tumor aggressiveness in papillary thyroid carcinoma

H Fu, C Ma, W Guan, W Cheng, F Feng… - OncoTargets and …, 2016 - Taylor & Francis
Aim The aim of this study was to assess if the expression of Notch 1 receptor is associated
with tumor aggressiveness in papillary thyroid carcinomas (PTCs). Patients and methods By …

[HTML][HTML] TSHR 基因甲基化与PTC 的关系研究

于波, 徐宁, 孙玺媛, 樊伟业, 姚佳兴, 李松埔… - World Journal of …, 2023 - hanspub.org
甲状腺癌是头颈部较为常见的恶性肿瘤, 发病率在全球范围内呈上升趋势,
病理类型以甲状腺乳头状癌(Papillary Thyroid Carcinoma, PTC) 最为常见. 促甲状腺激素受体 …

Mapping fundamental life elements in papillary thyroid carcinoma tissue

L Merolle, M Ragazzi, A Gianoncelli… - Journal of …, 2018 - iopscience.iop.org
Well-differentiated papillary thyroid carcinomas (PTCs) are the most common type of thyroid
cancer. Thyroid function depends on the presence of certain trace elements necessary for …

[引用][C] 甲状腺乳头状癌中TSHR 与NIS 基因启动子区甲基化状态与侵袭性相关性研究

许敬, 郭新海, 葛明华 - 中国现代医生, 2016