The worldwide rising prevalence of obesity and insulin resistance is associated with a
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …

The essential oil extracted from the black Piper nigrum L.(BPEO) was analyzed for
antioxidant, hepatoprotective and antifungal activities. BPEO is rich in total phenolics, total …

Application of nanomaterials in our daily life is increasing, day in day out and concerns have
raised about their toxicity for human and other organisms. In this manner, carbon-based …

Bioenergetic dysfunction is emerging as a cornerstone for establishing a framework for
understanding the pathophysiology of cardiovascular disease, diabetes, cancer and …

The use of many halogenated alkanes such as carbon tetrachloride (CCl4), chloroform
(CHCl3) or iodoform (CHI3), has been banned or severely restricted because of their distinct …

The neurodegeneration that occurs in sporadic Alzheimer's disease (AD) is consistently
associated with a number of characteristic histopathological, molecular, and biochemical …

Drug-induced hepatic injury accounts for more than 50 percent of cases of acute liver failure
in the United States. More than 75 percent of idiosyncratic drug reactions result in liver …

Numerous investigations have shown that mitochondrial dysfunction is a major mechanism
of drug-induced liver injury, which involves the parent drug or a reactive metabolite …

Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …

Leukocyte migration into and through tissues is fundamental to normal physiology,
immunopathology and host defence. Leukocyte entry into the central nervous system (CNS) …