Hepatotoxicity of chemotherapeutic agents such as methotrexate, oxaliplatin, and irinotecan
have been well documented and characterized allowing for careful management by …

Organophosphorus compounds may induce oxidative stress leading to generation of free
radicals and alterations in antioxidant and scavengers of oxygen free radicals (OFRs). The …

Hepatic inflammation is a common finding during a variety of liver diseases including drug-
induced liver toxicity. The inflammatory phenotype can be attributed to the innate immune …

Potato peel waste—its nutraceutical, industrial and biotechnological applacations Page 1
Potato peel waste—its nutraceutical, industrial and biotechnological applacations AUTHOR(S) …

The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

Oxidative stress is a core abnormality responsible for disease progression in nonalcoholic
fatty liver disease (NAFLD). However, the pathways that contribute to oxidative damage in …

ETHNOPHARMACOLOGICAL RELEVANCE: In traditional Indian medicine, all parts of
Emblica officinalis Gaertn plant including the fruit, seed, leaves, root, bark and flowers are …

Background & Aims: The Wnt/β-catenin pathway plays a role in liver growth and
development. To address this conclusively, we used a conditional knockout approach to …

One of the major mechanisms of drug-induced liver injury includes mitochondrial
perturbation and dysfunction. This is not a surprise, given that mitochondria are essential …

Accumulation of bile acids is a major mediator of cholestatic liver injury. Recent studies
indicate bile acid composition between humans and rodents is dramatically different, as …