Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …

Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …

Parkinson's disease (PD) is a progressive and debilitating chronic disease that affects more
than six million people worldwide, with rising prevalence. The hallmarks of PD are motor …

Among the popular animal models of Parkinson's disease (PD) commonly used in research
are those that employ neurotoxins, especially 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

Increasing evidence indicates a possible causal link between neuroinflammation and
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Ageing is a complex process, induced by multifaceted interaction of genetic, epigenetic, and
environmental factors. It is manifested by a decline in the physiological functions of …

Mitochondrial dysfunction and oxidative stress characterize major factors involved in the
activation of complex processes corresponding to apoptosis‐mediated neuronal …

Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Neurodegenerative diseases (NDs) represent a common neurological pathology that
determines a progressive deterioration of the brain or the nervous system. For treating NDs …