Oxidative stress is implicated in the pathogenesis of essential hypertension, a risk factor for
cardiovascular morbidity and mortality. Tomato carotenoids such as lycopene and the …

The etiological factors of oral cancer are complex including drinking alcohol, smoking
tobacco, betel quid chewing, human papillomavirus infection, and nutritional deficiencies …

The complex system of molecular communications underlying cell biochemistry and function
includes numerous components, kinases, phosphatases and transcription factors, that have …

Aberrant activation of the nuclear factor kappa B (NFkB) transcription system contributes to
cancer progression, and has a harmful effect on bone health. Several major components of …

We investigated the cytotoxic activities of crocin and crocetin, 2 major carotenoids isolated
from the stigma of Crocus sativus (saffron), on 5 human cancer cell lines and proposed their …

Carotenoids have been constantly investigated since the early fifty for their chemical,
biochemical and biological properties being presence in foods. Among the more than 1100 …

ABSTRACT A series of dietary ingredients and metabolites are able to induce an adaptive
stress response either by generation of reactive oxygen species (ROS) and/or via activation …

Carotenoid pigments are abundant in plants mainly in flowers and fruits and have diverse
roles in photobiology, photochemistry, and medicine. Carotenoids properties, such as …

Classic nutrition believed that healthy diets should simply provide sufficient antioxidant
loads to organisms, to hamper free radical processes and avoid oxidative stress. Current …

The transcription factor NRF2 (nuclear factor-E2-related factor 2) orchestrates major cellular
defense mechanisms including phase-II detoxification, inflammatory signaling, DNA repair …