Carotenoid cleavage dioxygenase 1 and its application for the production of C13-apocarotenoids in microbial cell factories: A review

Z Qi, X Tong, Y Zhang, S Jia, X Fang… - Journal of Agricultural …, 2023 - ACS Publications
C13-apocarotenoids are naturally derived from the C9–C10 (C9′–C10′) double-bond
cleavage of carotenoids by carotenoid cleavage dioxygenases (CCDs). As high-value …

Comparison of chemical structures and cytoprotection abilities between direct and indirect antioxidants

S Joko, M Watanabe, H Fuda, S Takeda… - Journal of Functional …, 2017 - Elsevier
To study structural and biological relationships in antioxidants, the cytoprotection,
cytotoxicity, and Keap1–Nrf2 pathway activation potentials of nine natural antioxidants were …

[PDF][PDF] Are lycopene metabolites metabolically active?

N Ford, J Erdman - Acta Biochimica Polonica, 2012 - frontierspartnerships.org
Lycopene is the most abundant carotenoid found in tomatoes and thus has been touted as
the bioactive component for the reduced risk of chronic diseases such as prostate cancer …

Lycopene supplementation: effects on oxidative stress, sex hormones, gonads and thyroid tissue in tilapia Oreochromis niloticus during Harness® exposure

RF Ismail, M Hamed, AEDH Sayed - Frontiers in Physiology, 2023 - frontiersin.org
Harness® is a commercial herbicide that contains acetochlor at a concentration of 84% as
an active ingredient. Ubiquitous, persistent, and substantial uses of Harness® in agricultural …

[HTML][HTML] β-Carotene inhibits activation of NF-κB, activator protein-1, and STAT3 and regulates abnormal expression of some adipokines in 3T3-L1 adipocytes

SO Cho, MH Kim, H Kim - Journal of cancer prevention, 2018 - ncbi.nlm.nih.gov
Background Oxidative stress occurs in white adipose tissue and dysregulates the
expression of adipokines secreted from adipocytes. Since adipokines influence …

[HTML][HTML] Keap1-Nrf2-ARE 信号通路及其激活剂的研究进展

姚娟, 吴平安, 李芸, 李越峰, 刘东玲, 刘雪枫 - 2019 - html.rhhz.net
Keap1-Nrf2-ARE 信号通路是细胞防御氧化应激损伤的最重要机制之一. 许多具有解毒,
抗氧化防御功能的蛋白质, 其转录调控都依赖于Nrf2 信号通路的激活. 研究表明, Nrf2 …

A MUFA/carotenoid-rich oil ameliorated insulin resistance by improving inflammation and oxidative stress in obese rats

LG Moreno, NR César, DS Melo, MTO Figueiró… - Molecular and Cellular …, 2024 - Elsevier
Highlights•Pequi oil is a carotenoid/monounsaturated fatty acid-rich food with antioxidant
and anti-inflammatory properties.•Pequi oil reduced adipose tissue and hepatic fat …

Role of lycopene in the control of ROS-mediated cell growth: implications in cancer prevention

P Palozza, N Parrone, R Simone… - Current medicinal …, 2011 - ingentaconnect.com
Dietary intakes of tomatoes and tomato products containing lycopene have been shown to
be associated with decreased risk of chronic diseases, such as cancer. Although several …

Carotenoids, chronic disease prevention and dietary recommendations

T Bohn - Int. J. Vitam. Nutr. Res, 2017 - econtent.hogrefe.com
Carotenoids are C-30, C-40 or C-50 terpenoids produced by a number of bacteria, fungi,
and plants. In addition to acting as vitamin A precursors such as β-carotene, their dietary …

Apo-8′-lycopenal induces expression of HO-1 and NQO-1 via the ERK/p38-Nrf2-ARE pathway in human HepG2 cells

CM Yang, SM Huang, CL Liu… - Journal of agricultural and …, 2012 - ACS Publications
Lycopene and its metabolite apo-10′-lycopenoic acid have been shown to induce phase II
detoxifying/antioxidant enzymes through activation of the nuclear factor erythroid-derived 2 …