BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

Gene methylation in thyroid tumorigenesis

M Xing - Endocrinology, 2007 - academic.oup.com
Aberrant gene methylation plays an important role in human tumorigenesis, including
thyroid tumorigenesis. Many tumor suppressor genes are aberrantly methylated in thyroid …

Diagnostic value of serum thyroglobulin measurements in the follow‐up of differentiated thyroid carcinoma, a structured meta‐analysis

CFA Eustatia‐Rutten, JWA Smit, JA Romijn… - Clinical …, 2004 - Wiley Online Library
Summary objective To investigate to what extent thyroid remnant ablation and withdrawal
from thyroxine are required to achieve sufficient accuracy of serum thyroglobulin (Tg) …

Methylation of the Thyroid-stimulating Hormone Receptor Gene in Epithelial Thyroid Tumors: A Marker of Malignancy and a Cause of Gene Silencing

M Xing, H Usadel, Y Cohen, Y Tokumaru, Z Guo… - Cancer research, 2003 - AACR
Thyroid-stimulating hormone receptor (TSHR) expression is frequently silenced in epithelial
thyroid cancers associated with decreased or absent TSH-promoted iodine uptake. To study …

Imaging and dosimetry for alpha-particle emitter radiopharmaceutical therapy: improving radiopharmaceutical therapy by looking into the black box

G Sgouros, E Frey, Y Du, R Hobbs, W Bolch - European Journal of …, 2021 - Springer
Radiopharmaceutical therapy using α-particle emitting radionuclides (αRPT) is a novel
treatment modality that delivers highly potent alpha-particles to cancer cells or their …

Peroxisomal proliferator-activated receptor-γ agonists induce partial reversion of epithelial-mesenchymal transition in anaplastic thyroid cancer cells

A Aiello, G Pandini, F Frasca, E Conte… - …, 2006 - academic.oup.com
Anaplastic thyroid cancer (ATC) is an extremely aggressive tumor characterized by marked
epithelial mesenchymal transition, which leads, almost invariably, to death. Peroxisomal …

Combined effects of baicalein and docetaxel on apoptosis in 8505c anaplastic thyroid cancer cells via downregulation of the ERK and Akt/mTOR pathways

CH Park, SE Han, IS Nam-Goong… - Endocrinology and …, 2018 - synapse.koreamed.org
Background Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies.
Docetaxel, a microtubule stabilizer, is a common chemotherapeutic agent used to treat …

Thyroglobulin: a specific serum marker for the management of thyroid carcinoma

RJ Whitley, KB Ain - Clinics in laboratory medicine, 2004 - labmed.theclinics.com
Thyroid carcinoma is diagnosed in about 22,000 people each year in the United States [1].
More than 90% of thyroid carcinomas, including papillary and follicular cancers, are well …

Recent advances in molecular biology of thyroid cancer and their clinical implications

M Xing - Otolaryngologic Clinics of North America, 2008 - Elsevier
Thyroid cancer is the most common endocrine malignancy. With a rapidly rising incidence in
recent years, novel efficient management strategies are increasingly needed for this cancer …

Dermatologic aspects of thyroid disease

KD Burman, L McKinley-Grant - Clinics in dermatology, 2006 - Elsevier
Thyroid disorders commonly have dermatologic manifestations. The purpose of the present
chapter is to review and emphasize potential clinical dermatologic findings that can occur …