Over the last decade, the concept of targeted biological therapy for the treatment of cancer
has emerged. However, a better understanding of these targets and their role in tumor cells …

Oxaborole-based polymers are stimuli-responsive materials that can reversibly interact with
diols at pH values higher than their p K a. The strong binding of the oxaborole with cis …

Recent advances in basic and clinical oncology have led to the identification and
characterization of several deregulated gene products involved in cancer progression to …

Multiple signal transduction pathways play a crucial role in cancer development,
progression, and response to different therapies. An important issue is whether common …

We show the efficacy of a therapeutic strategy that combines the potency of a DNA-binding
photosensitizer, UVA Sens, with the tumor-targeting potential of receptor-mediated …

It is of major importance to overcome the immunological tolerance in attempts to generate
efficient tumour vaccines. Here, we describe induction of autoantibodies and self‐reactive …

2010-06-02 Assigned to FOX CHASE CANCER CENTER reassignment FOX CHASE
CANCER CENTER ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Over the past 30 years a huge amount of information has been gathered about tumour
biology and the carcinogenic process. It is known that cancer develops as a result of a …

Background: Tumor growth and progression depend largely on the activity of cell membrane
receptors like epidermal growth factor receptor (EGFR). This receptor plays a significant role …

ZRKFYGHZFMAOKI-QMGMOQQFSA-N Tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …