[HTML][HTML] Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy

AVA Mariadoss, AS Sivakumar, CH Lee… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a collection of metabolic and pathophysiological disorders
manifested with high glucose levels in the blood due to the inability of β-pancreatic cells to …

Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

Immunomodulatory biomaterials for implant-associated infections: from conventional to advanced therapeutic strategies

J Dong, W Wang, W Zhou, S Zhang, M Li, N Li… - Biomaterials …, 2022 - spj.science.org
Implant-associated infection (IAI) is increasingly emerging as a serious threat with the
massive application of biomaterials. Bacteria attached to the surface of implants are often …

Tantalum and its derivatives in orthopedic and dental implants: Osteogenesis and antibacterial properties

X Wang, B Ning, X Pei - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Implant-associated infections and aseptic loosening are some of the main reasons for
implant failure. Therefore, there is an urgent need to improve the osseointegration and …

Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

Polydopamine‐mediated interfacial functionalization of implants for accelerating infected bone repair through light‐activatable antibiosis and carbon monoxide gas …

Z Yuan, J Wu, Z Fu, S Meng, L Dai… - Advanced Functional …, 2022 - Wiley Online Library
Current treatments for implant‐associated infection remain unsatisfactory due to secondary
infection and excessive inflammation, which impairs osseointegration. Herein, an interfacial …

[HTML][HTML] Additively manufactured biodegradable porous magnesium implants for elimination of implant-related infections: An in vitro and in vivo study

K Xie, N Wang, Y Guo, S Zhao, J Tan, L Wang, G Li… - Bioactive materials, 2022 - Elsevier
Magnesium (Mg) alloys that have both antibacterial and osteogenic properties are suitable
candidates for orthopedic implants. However, the fabrication of ideal Mg implants suitable for …

Ultrafast in-situ forming halloysite nanotube-doped chitosan/oxidized dextran hydrogels for hemostasis and wound repair

Z Li, B Li, X Li, Z Lin, L Chen, H Chen, Y Jin… - Carbohydrate …, 2021 - Elsevier
A series of halloysite nanotube (HNT)-doped chitosan (CS)/oxidized dextran (ODEX)
adhesive hydrogels were developed through a Schiff base reaction. The resultant …

Topography‐supported nanoarchitectonics of hybrid scaffold for systematically modulated bone regeneration and remodeling

TS Jang, SJ Park, JE Lee, J Yang… - Advanced Functional …, 2022 - Wiley Online Library
Orthopedic implants should have sufficient strength and promote bone tissue regeneration.
However, most conventional implants are optimized for use either under high mechanical …

Photosensitizer Nanodot Eliciting Immunogenicity for Photo‐Immunologic Therapy of Postoperative Methicillin‐Resistant Staphylococcus aureus Infection and …

H Tang, X Qu, W Zhang, X Chen, S Zhang… - Advanced …, 2022 - Wiley Online Library
The treatment of postoperative infection caused by multidrug‐resistant bacteria, such as
methicillin‐resistant Staphylococcus aureus (MRSA), has become an intractable clinical …