Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

Angiogenesis is the growth of new capillaries from the preexisting blood vessels.
Glioblastoma (GBM) tumors are highly vascularized tumors, and glioma growth depends on …

The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …

The pathophysiology and treatment of depression have been the focus of intense research
and while there is much that remains unknown, modern neurobiological approaches are …

Following injury, the oral mucosa undergoes complex sequences of biological healing
processes to restore homeostasis. While general similarities exist, there are marked …

The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

Tumor microenvironment is a complex system that contains multiple cells and cytokines.
Among the multiple immune cells, macrophage is particularly abundant and plays an …

Vascular endothelial growth factor-A (VEGF) is one of the most important growth factors for
regulation of vascular development and angiogenesis. Since bone is a highly vascularized …

Pre-eclampsia is a pregnancy-specific disorder that has a worldwide prevalence of 5-8%. It
is one of the main causes of maternal and perinatal morbidity and mortality globally and …

Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …