Corticotropin-releasing hormone (CRH) plays a central role in the regulation of the
hypothalamic-pituitary-adrenal (HPA)-axis, ie, the final common pathway in the stress …

Menopause is diagnosed after 12 months of amenorrhoea resulting from the permanent
cessation of ovarian function. The mean age at menopause is 51 years. The …

The stress response is mediated by the hypothalamo–pituitary–adrenal (HPA) system.
Activity of the corticotropin-releasing hormone (CRH) neurons in the hypothalamic …

Possible differences between men and women in age-related patterns of hypothalamic–
pituitary–adrenal (HPA) axis response to challenge were examined to test the hypothesis …

Compelling evidence now exists for estrogen's involvement in the regulation of mood and
cognitive functions. Serum estrogen levels have been shown to play an important role in the …

The steroid hormone estrogen influences brain function and neuropsychiatric disorders, but
neuroanatomical information about the estrogen receptors (ERs) are rather limited. The …

Objective Previous studies have found increased rates of depression in women aged 45 to
54 years, but the factors that influence these rates are not understood. It was assessed …

Objective To address the association between depression and absolute levels of estradiol,
and change in estradiol, among women during the menopausal transition. Methods This …

Sex steroid hormones exert profound effects on mood and mental state. Thus, in women,
oestrogen is thought to protect against depression and delay the onset of schizophrenia and …

Abstract 17β-Estradiol (E 2) may influence anxiety behavior; however, its effects and
mechanisms are not well understood. To determine whether E 2's effects on anxiety …