Pathogenesis of brain edema and investigation into anti-edema drugs

S Michinaga, Y Koyama - International journal of molecular sciences, 2015 - mdpi.com
Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …

A review of progress in understanding the pathophysiology and treatment of brain edema

A Marmarou - Neurosurgical focus, 2007 - thejns.org
Object Brain edema resulting from traumatic brain injury (TBI) or ischemia if uncontrolled
exhausts volume reserve and leads to raised intracranial pressure and brain herniation. The …

[PDF][PDF] The cellular mechanisms of neuronal swelling underlying cytotoxic edema

RL Rungta, HB Choi, JR Tyson, A Malik… - Cell, 2015 - cell.com
Cytotoxic brain edema triggered by neuronal swelling is the chief cause of mortality
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …

The role of PLVAP in endothelial cells

L Denzer, W Muranyi, H Schroten, C Schwerk - Cell and Tissue Research, 2023 - Springer
Endothelial cells play a major part in the regulation of vascular permeability and
angiogenesis. According to their duty to fit the needs of the underlying tissue, endothelial …

Antiedema therapy in ischemic stroke

J Bardutzky, S Schwab - Stroke, 2007 - Am Heart Assoc
Life-threatening, space-occupying brain edema occurs in up to 10% of patients with
supratentorial infarcts and is traditionally associated with a high mortality rate of up to 80 …

The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for …

EK Bosma, CJF van Noorden… - Fluids and Barriers of …, 2018 - Springer
Breakdown of the blood–brain barrier (BBB) or inner blood–retinal barrier (BRB), induced by
pathologically elevated levels of vascular endothelial growth factor (VEGF) or other …

Medical management of cerebral edema

A Raslan, A Bhardwaj - Neurosurgical focus, 2007 - thejns.org
✓ Cerebral edema is frequently encountered in clinical practice in critically ill patients with
acute brain injury from diverse origins and is a major cause of increased morbidity and …

Mannitol for acute stroke

D Bereczki, M Liu, GF do Prado… - Cochrane Database of …, 2007 - cochranelibrary.com
Background Mannitol is an osmotic agent and a free radical scavenger which might
decrease oedema and tissue damage in stroke. Objectives To test whether treatment with …

[图书][B] Forensic neuropathology

JE Leestma - 2014 - books.google.com
A timely update to a classic reference, this volume presents an encyclopedic exposition of
neuropathological conditions that may have forensic import. It includes expanded sections …

Cerebral edema

ML Ho, R Rojas, RL Eisenberg - American Journal of …, 2012 - Am Roentgen Ray Soc
T his article reviews the pathophysiology and imaging appearances of cerebral edema or
increased water content. Edema is a common response to various forms of brain injury, and …