miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
Clinical significance of FBXW7 loss of function in human cancers
J Fan, M Bellon, M Ju, L Zhao, M Wei, L Fu, C Nicot - Molecular cancer, 2022 - Springer
Abstract FBXW7 (F-Box and WD Repeat Domain Containing 7)(also referred to as FBW7 or
hCDC4) is a component of the Skp1-Cdc53/Cullin-F-box-protein complex (SCF/β-TrCP). As …
hCDC4) is a component of the Skp1-Cdc53/Cullin-F-box-protein complex (SCF/β-TrCP). As …
The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …
constitutive expression of viral oncogenes have been recognized as the main cause of the …
LncRNA MT1JP functions as a ceRNA in regulating FBXW7 through competitively binding to miR-92a-3p in gastric cancer
G Zhang, S Li, J Lu, Y Ge, Q Wang, G Ma, Q Zhao… - Molecular cancer, 2018 - Springer
Background Emerging evidence has shown that dysregulation function of long non-coding
RNAs (lncRNAs) implicated in gastric cancer (GC). However, the role of the differentially …
RNAs (lncRNAs) implicated in gastric cancer (GC). However, the role of the differentially …
microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer
JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …
could be observed in women who infected with papillomavirus, regular oral contraceptives …
FBXW7 in cancer: what has been unraveled thus far?
The FBXW7 (F-box with 7 tandem WD40) protein encoded by the gene FBXW7 is one of the
crucial components of ubiquitin ligase called Skp1-Cullin1-F-box (SCF) complex that aids in …
crucial components of ubiquitin ligase called Skp1-Cullin1-F-box (SCF) complex that aids in …
Recent insight into the role of FBXW7 as a tumor suppressor
K Yumimoto, KI Nakayama - Seminars in cancer biology, 2020 - Elsevier
FBXW7 (also known as Fbw7, Sel10, hCDC4, or hAgo) is a tumor suppressor and the most
frequently mutated member of the F-box protein family in human cancers. FBXW7 functions …
frequently mutated member of the F-box protein family in human cancers. FBXW7 functions …
[HTML][HTML] F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects
DS Tekcham, D Chen, Y Liu, T Ling, Y Zhang… - Theranostics, 2020 - ncbi.nlm.nih.gov
E3 ubiquitin ligases play a critical role in cellular mechanisms and cancer progression. F-
box protein is the core component of the SKP1-cullin 1-F-box (SCF)-type E3 ubiquitin ligase …
box protein is the core component of the SKP1-cullin 1-F-box (SCF)-type E3 ubiquitin ligase …
The role of miRNAs in the invasion and metastasis of cervical cancer
J Wang, L Chen - Bioscience reports, 2019 - portlandpress.com
Cervical cancer (CC) with early metastasis of the primary tumor results in poor prognosis
and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules …
and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules …
MicroRNAs in gynecological cancers: Small molecules with big implications
Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy
of available therapeutic options. Thus, there remains an urgent and unmet need for …
of available therapeutic options. Thus, there remains an urgent and unmet need for …