GATA family proteins play essential roles in development of many cell types, including
hematopoietic, cardiac, and endodermal lineages. The first three factors, GATAs 1, 2, and 3 …

Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …

From the bestselling author, Barbara J. Bain, the new edition of this practical reference on
the principles of leukaemia diagnosis and classification has been fully updated, and …

Platelets are anuclear blood cells required for haemostasis and are implicated in other
processes including inflammation and metastasis. Platelets are produced by …

Cytogenetic abnormalities and early response to treatment are the main prognostic factors in
acute myeloid leukemia (AML). Recently, NUP98/NSD1 (t (5; 11)(q35; p15)), a …

The role of allogeneic hematopoietic stem cell transplantation (HCT) in the treatment of
acute myelogenous leukemia (AML) in children is reviewed and critically evaluated in this …

The outcome for children with acute myeloid leukemia (AML) has improved significantly over
the past 30 years, with complete remission and overall survival rates exceeding 90 and …

PURPOSE Increased CD123 surface expression has been associated with high-risk
disease characteristics in adult acute myeloid leukemia (AML), but has not been well …

Structural and numerical alterations of chromosome 21 are extremely common in
hematological malignancies. While the functional impact of chimeric transcripts from fused …

Genetic abnormalities and early treatment response are the main prognostic factors in acute
myeloid leukemia (AML). Acute megakaryoblastic leukemia (AMKL) is a rare subtype of …