A wide range of nitric oxide (NO)-releasing materials has emerged as potential therapeutics
that exploit NO's vast biological roles. Macromolecular NO-releasing scaffolds are …

The majority of current infectious diseases are almost untreatable by conventional antibiotic
therapy given the advent of multidrug-resistant bacteria. The degree of severity and the …

The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic
resistance and relatively few novel compounds or strategies under development or entering …

Nanotechnology is providing new ways to manipulate the structure and chemistry of
surfaces to inhibit bacterial colonization. In this study, we evaluated the ability of glass slides …

Background: Osteomyelitis is an inflammatory disorder of bone caused by infection leading
to necrosis and destruction. It can affect all ages and involve any bone. Osteomyelitis may …

Staphylococcus aureus is a Gram-positive pathogen that causes potentially life-threatening
nosocomial-and community-acquired infections, such as osteomyelitis and endocarditis …

Bacterial biofilms are particularly problematic since they become resistant to most available
antibiotics. Hence, novel potential antagonists to inhibit biofilm formation are urgent. Here …

Biofilms are sessile communities of microbial cells contained within a self-produced
exopolymeric matrix. Bacteria encased in biofilms exhibit upwards of 10–1000-fold higher …

Bacteria are able to adapt to undesirable changes in nutrient availability, environmental
conditions and presence of antimicrobial products, as well as to immunological defenses …

Infectious complications of open fractures continue to be a significant factor contributing to
non-osseous union and extremity amputation. The persistence of bacteria within biofilms …