TGF-β pathways in aging and immunity: lessons from Caenorhabditis elegans
KK Yamamoto, C Savage-Dunn - Frontiers in Genetics, 2023 - frontiersin.org
The Transforming Growth Factor-β (TGF-β) superfamily of signaling molecules plays critical
roles in development, differentiation, homeostasis, and disease. Due to the conservation of …
roles in development, differentiation, homeostasis, and disease. Due to the conservation of …
The Caenorhabditis elegans cuticle and precuticle: a model for studying dynamic apical extracellular matrices in vivo
MV Sundaram, N Pujol - Genetics, 2024 - academic.oup.com
Apical extracellular matrices (aECMs) coat the exposed surfaces of animal bodies to shape
tissues, influence social interactions, and protect against pathogens and other …
tissues, influence social interactions, and protect against pathogens and other …
TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3-and Foxp3-mediated transcriptional networks
Q Zhang, M Geng, K Li, H Gao, X Jiao, K Ai… - Journal of Biological …, 2023 - ASBMB
Transforming growth factor-β1 (TGF-β1) can suppress the activation, proliferation, and
function of many T-cell subsets, protecting organisms from inflammatory and autoimmune …
function of many T-cell subsets, protecting organisms from inflammatory and autoimmune …
Evolution and diversity of TGF-β pathways are linked with novel developmental and behavioral traits
Transforming growth factor-β (TGF-β) signaling is essential for numerous biologic functions.
It is a highly conserved pathway found in all metazoans including the nematode …
It is a highly conserved pathway found in all metazoans including the nematode …
Condensed tannins act as anthelmintics by increasing the rigidity of the nematode cuticle
L Greiffer, E Liebau, FC Herrmann, V Spiegler - Scientific Reports, 2022 - nature.com
Tannins and tanniferous plant extracts have been discussed as sustainable means for
helminth control in the past two decades in response to a dramatic increase of resistances …
helminth control in the past two decades in response to a dramatic increase of resistances …
Advancing insights into microgravity induced muscle changes using Caenorhabditis elegans as a model organism
Spaceflight presents significant challenges to the physiological state of living organisms.
This can be due to the microgravity environment experienced during long-term space …
This can be due to the microgravity environment experienced during long-term space …
ADARs regulate cuticle collagen expression and promote survival to pathogen infection
Background In all organisms, the innate immune system defends against pathogens through
basal expression of molecules that provide critical barriers to invasion and inducible …
basal expression of molecules that provide critical barriers to invasion and inducible …
Regulation of miR-61 and col-19 via TGF-β and Notch signalling in Caenorhabditis elegans against Klebsiella aerogenes infection
T Gowripriya, KM Afrin, M Paurna, R Yashwanth… - Microbial …, 2024 - Elsevier
Klebsiella aerogenes, previously known as Enterobacter aerogenes, is a gram-negative
bacterium typically present in the gastrointestinal tract. While numerous studies reported the …
bacterium typically present in the gastrointestinal tract. While numerous studies reported the …
An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease
M Schvarzstein, F Alam, M Toure… - Journal of Developmental …, 2023 - mdpi.com
Whole genome duplication (WGD) or polyploidization can occur at the cellular, tissue, and
organismal levels. At the cellular level, tetraploidization has been proposed as a driver of …
organismal levels. At the cellular level, tetraploidization has been proposed as a driver of …
Transforming growth factor‐β family biology: From basic mechanisms to roles in development and disease.
JL Christian, CS Hill - Developmental Dynamics, 2022 - search.ebscohost.com
Beginning with the ligands, Rifkin et al. 1 discuss the latent TGF-binding proteins (LTBPs)
with respect to their role in regulating TGF-ligand activity. The transforming growth factor …
with respect to their role in regulating TGF-ligand activity. The transforming growth factor …