Obesity and the risk of cardiometabolic diseases
PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …
of adults in Westernized countries have obesity. Recognized as a major health concern …
Obesity, risk of diabetes and role of physical activity, exercise training and cardiorespiratory fitness
The epidemic of obesity contributes to the burden of type 2 diabetes mellitus (T2DM) in the
United States and worldwide. Importantly, obesity is not only preventable but can be treated …
United States and worldwide. Importantly, obesity is not only preventable but can be treated …
Therapeutic landscape for NAFLD in 2020
BA Neuschwander-Tetri - Gastroenterology, 2020 - Elsevier
Lifestyle modifications focused on healthy eating and regular exercise are the primary
recommendations for patients with nonalcoholic steatohepatitis (NASH). However, for …
recommendations for patients with nonalcoholic steatohepatitis (NASH). However, for …
Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss
BØ Christoffersen, G Sanchez‐Delgado, LM John… - …, 2022 - Wiley Online Library
New appetite‐regulating antiobesity treatments such as semaglutide and agents under
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …
[HTML][HTML] OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21
RO Pereira, A Marti, AC Olvera, SM Tadinada… - Elife, 2021 - elifesciences.org
Adrenergic stimulation of brown adipocytes alters mitochondrial dynamics, including the
mitochondrial fusion protein optic atrophy 1 (OPA1). However, direct mechanisms linking …
mitochondrial fusion protein optic atrophy 1 (OPA1). However, direct mechanisms linking …
Impact of estrogens on resting energy expenditure: A systematic review
S Weidlinger, K Winterberger, J Pape… - Obesity …, 2023 - Wiley Online Library
The fear of weight gain is one of the main reasons for women not to initiate or to early
discontinue hormonal contraception or menopausal hormone therapy. Resting energy …
discontinue hormonal contraception or menopausal hormone therapy. Resting energy …
[HTML][HTML] The evolving view of thermogenic fat and its implications in cancer and metabolic diseases
X Yin, Y Chen, R Ruze, R Xu, J Song… - Signal Transduction and …, 2022 - nature.com
The incidence of metabolism-related diseases like obesity and type 2 diabetes mellitus has
reached pandemic levels worldwide and increased gradually. Most of them are listed on the …
reached pandemic levels worldwide and increased gradually. Most of them are listed on the …
Beyond the bone: Bone morphogenetic protein signaling in adipose tissue
AM Blázquez‐Medela, M Jumabay… - Obesity …, 2019 - Wiley Online Library
The bone morphogenetic proteins (BMPs) belong to the same superfamily as related to
transforming growth factor β (TGFβ), growth and differentiation factors (GDFs), and activins …
transforming growth factor β (TGFβ), growth and differentiation factors (GDFs), and activins …
[HTML][HTML] MicroRNA cues from nature: a roadmap to decipher and combat challenges in human health and disease?
MicroRNAs are small non-coding RNA (18–24 nt long) that fine-tune gene expression at the
post-transcriptional level. With the advent of “multi-omics” analysis and sequencing …
post-transcriptional level. With the advent of “multi-omics” analysis and sequencing …
Omega‐6 and omega‐3 oxylipins as potential markers of cardiometabolic risk in young adults
Abstract Objective Omega‐6 and omega‐3 oxylipins are known to play a role in
inflammation and cardiometabolic diseases in preclinical models. The associations between …
inflammation and cardiometabolic diseases in preclinical models. The associations between …