Cardiovascular diseases (CVD) are the leading cause of death worldwide and display
complex phenotypic heterogeneity caused by many convergent processes, including …

In recent times, there have been notable changes in cardiovascular medicine, propelled by
the swift advancements in artificial intelligence (AI). The present work provides an overview …

Abstract Background Circular RNAs (circRNAs), a novel class of non-coding RNAs, play an
important regulatory role in pulmonary arterial hypertension (PAH); however, the specific …

Background Pulmonary arterial hypertension (PAH) exhibits phenotypic heterogeneity and
variable response to therapy. The metabolome has been implicated in the pathogenesis of …

Introduction Pulmonary arterial hypertension (PAH) is a progressive and life-threatening
disease. Approved treatment options currently primarily target abnormal cell signaling …

Pulmonary arterial hypertension (PAH) is a devastating vascular disease with multiple
etiologies. Emerging evidence supports a fundamental role for epigenetic machinery and …

A major gap in diagnosis, classification, risk stratification, and prediction of therapeutic
response exists in pulmonary arterial hypertension (PAH), driven in part by a lack of …

Pulmonary arterial hypertension (PAH) is characterized by progressive vascular remodeling
caused by the excessive proliferation and survival of pulmonary artery smooth muscle cells …

Pulmonary arterial hypertension (PAH) is a group of severe, progressive, and debilitating
diseases with limited therapeutic options. This study aimed to explore novel therapeutic …

Diseases of the lung account for more than 5 million deaths worldwide and are a healthcare
burden. Improving clinical outcomes, including mortality and quality of life, involves a holistic …