Engineering, applications, and future perspectives of GPCR‐based genetically encoded fluorescent indicators for neuromodulators
VL Rohner, PJ Lamothe‐Molina… - Journal of …, 2024 - Wiley Online Library
This review explores the evolving landscape of G‐protein‐coupled receptor (GPCR)‐based
genetically encoded fluorescent indicators (GEFIs), with a focus on their development …
genetically encoded fluorescent indicators (GEFIs), with a focus on their development …
[HTML][HTML] Central amygdala CRF+ neurons promote heightened threat reactivity following early life adversity in mice
C Demaestri, M Pisciotta, N Altunkeser, G Berry… - Nature …, 2024 - nature.com
Failure to appropriately predict and titrate reactivity to threat is a core feature of fear and
anxiety-related disorders and is common following early life adversity (ELA). A population of …
anxiety-related disorders and is common following early life adversity (ELA). A population of …
Cell signaling in the circadian pacemaker: new insights from in vivo imaging
X Bonnefont - Neuroendocrinology, 2024 - karger.com
Background:“One for all, and all for one,” the famous rallying cry of the Three Musketeers, in
Alexandre Dumas's popular novel, certainly applies to the 20,000 cells composing the …
Alexandre Dumas's popular novel, certainly applies to the 20,000 cells composing the …
[HTML][HTML] Dopamine neurons drive spatiotemporally heterogeneous striatal dopamine signals during learning
Environmental cues, through Pavlovian learning, become conditioned stimuli that invigorate
and guide animals toward acquisition of rewards. Dopamine neurons in the ventral …
and guide animals toward acquisition of rewards. Dopamine neurons in the ventral …
[HTML][HTML] Protocol for fiber photometry recording from deep brain regions in head-fixed mice
S Zhou, S Duan, H Yang - STAR protocols, 2024 - Elsevier
To exclude the influence of motion on in vivo calcium imaging, animals usually need to be
fixed. However, the whole-body restraint can cause stress in animals, affecting experimental …
fixed. However, the whole-body restraint can cause stress in animals, affecting experimental …
[HTML][HTML] Recording the Brain in Vivo: Emerging Technologies for the Exploration of Mental Health Conditions: Mounting interest in mental health conditions over the …
T Free - BioTechniques, 2024 - Taylor & Francis
Recording the brain in vivo: emerging technologies for the exploration of mental health
conditions | BioTechniques Future Science Logo Search This Journal Anywhere Quick Search …
conditions | BioTechniques Future Science Logo Search This Journal Anywhere Quick Search …
An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology
Neurotechnologies and genetic tools for dissecting neural circuit functions have advanced
rapidly over the past decade, although the development of complementary pharmacological …
rapidly over the past decade, although the development of complementary pharmacological …
Depth-resolved fibre photometry for Alzheimer's disease plaque pathology in vivo
N Byron - 2024 - stax.strath.ac.uk
The progression of potential Alzheimer's disease (AD) treatments to the clinic may be
hindered by the pre-clinical screening approach used to access plaque-modifying effects in …
hindered by the pre-clinical screening approach used to access plaque-modifying effects in …
Automated device for simultaneous photometry and electrophysiology in freely moving animals
Photometry and electrophysiology are powerful tools for investigating brain-behavior
relationships. Combining these techniques would allow us to ask previously un-addressable …
relationships. Combining these techniques would allow us to ask previously un-addressable …
Obtaining artifact-corrected signals in fiber photometry: Isosbestic signals, robust regression and dF/F calculations
Fiber photometry is a powerful tool to measure a wide variety of brain dynamics from
targeted cells and circuits in freely-behaving animals. However, measured biosensor signals …
targeted cells and circuits in freely-behaving animals. However, measured biosensor signals …