Emerging roles of GluN3-containing NMDA receptors in the CNS

I Pérez-Otaño, RS Larsen, JF Wesseling - Nature Reviews …, 2016 - nature.com
GluN3-containing NMDA receptors (GluN3-NMDARs) are rarer than the'classical'NMDARs,
which are composed solely of GluN1 and GluN2 subunits, and have non-conventional …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

The role of the orbitofrontal cortex in alcohol use, abuse, and dependence

DE Moorman - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
One of the major functions of the orbitofrontal cortex (OFC) is to promote flexible motivated
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …

Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence

F Alasmari, S Goodwani, RE McCullumsmith… - Progress in …, 2018 - Elsevier
Emerging evidence demonstrates that alcohol dependence is associated with dysregulation
of several neurotransmitters. Alterations in dopamine, glutamate and gamma-aminobutyric …

Aging with alcohol-related brain damage: Critical brain circuits associated with cognitive dysfunction

PT Nunes, BT Kipp, NL Reitz, LM Savage - International review of …, 2019 - Elsevier
Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …

The neuroprotective effects of carvacrol on ethanol‐induced hippocampal neurons impairment via the antioxidative and antiapoptotic pathways

P Wang, Q Luo, H Qiao, H Ding, Y Cao… - Oxidative medicine …, 2017 - Wiley Online Library
Chronic alcohol consumption causes hippocampal neuronal impairment, which is
associated with oxidative stress and apoptosis. Carvacrol is a major monoterpenic phenol …

GluN3A NMDA receptor subunits: more enigmatic than ever?

O Crawley, MJ Conde‐Dusman… - The Journal of …, 2022 - Wiley Online Library
Non‐conventional N‐methyl‐d‐aspartate receptors (NMDARs) containing GluN3A subunits
have unique biophysical, signalling and localization properties within the NMDAR family …

Zebrafish shoaling, its behavioral and neurobiological mechanisms, and its alteration by embryonic alcohol exposure: a review

A Facciol, R Gerlai - Frontiers in behavioral neuroscience, 2020 - frontiersin.org
Social cognition and social behaviors are complex phenomena that involve numerous brain
areas and underlying neurobiological mechanisms. Embryonic alcohol exposure may lead …

Zonisamide, topiramate, and levetiracetam: efficacy and neuropsychological effects in alcohol use disorders

CM Knapp, DA Ciraulo, O Sarid-Segal… - Journal of clinical …, 2015 - journals.lww.com
The anticonvulsant topiramate not only decreases ethanol consumption in alcohol
dependence (AD) but also may produce several adverse events including cognitive …

Expression of glutamatergic genes in healthy humans across 16 brain regions; altered expression in the hippocampus after chronic exposure to alcohol or cocaine

MA Enoch, AA Rosser, Z Zhou, DC Mash… - Genes, Brain and …, 2014 - Wiley Online Library
We analyzed global patterns of expression in genes related to glutamatergic
neurotransmission (glutamatergic genes) in healthy human adult brain before determining …