Defining and combating antibiotic resistance from One Health and Global Health perspectives

S Hernando-Amado, TM Coque, F Baquero… - Nature …, 2019 - nature.com
Several interconnected human, animal and environmental habitats can contribute to the
emergence, evolution and spread of antibiotic resistance, and the health of these contiguous …

[HTML][HTML] Antibiotic resistance: moving from individual health norms to social norms in one health and global health

S Hernando-Amado, TM Coque, F Baquero… - Frontiers in …, 2020 - frontiersin.org
Antibiotic resistance is a problem for human health, and consequently, its study had been
traditionally focused toward its impact for the success of treating human infections in …

Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning

E Ong, MF Cooke, A Huffman, Z Xiang… - Nucleic acids …, 2021 - academic.oup.com
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV)
is a state-of-the-art technique to predict vaccine candidates from pathogen's genome (s). To …

[HTML][HTML] PanRV: Pangenome-reverse vaccinology approach for identifications of potential vaccine candidates in microbial pangenome

K Naz, A Naz, ST Ashraf, M Rizwan, J Ahmad… - BMC …, 2019 - Springer
Background A revolutionary diversion from classical vaccinology to reverse vaccinology
approach has been observed in the last decade. The ever-increasing genomic and …

Current status of pan-genome analysis for pathogenic bacteria

Y Kim, C Gu, HU Kim, SY Lee - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Wealth of genome data are making pan-genome analysis increasingly
possible.•Pan-genome analysis is an effective approach to understand pathogenic …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2023 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

[HTML][HTML] Identification of vaccine and drug targets in Shigella dysenteriae sd197 using reverse vaccinology approach

K Jalal, T Abu-Izneid, K Khan, M Abbas, A Hayat… - Scientific Reports, 2022 - nature.com
Shigellosis is characterized as diarrheal disease that causes a high mortality rate especially
in children, elderly and immunocompromised patients. More recently, the World Health …

[HTML][HTML] Chimeric vaccine designs against Acinetobacter baumannii using pan genome and reverse vaccinology approaches

F Shahid, T Zaheer, ST Ashraf, M Shehroz, F Anwer… - Scientific reports, 2021 - nature.com
Abstract Acinetobacter baumannii (A. baumannii), an opportunistic, gram-negative
pathogen, has evoked the interest of the medical community throughout the world because …

[HTML][HTML] Designing multi-antigen vaccines against Acinetobacter baumannii using systemic approaches

MJ McConnell, AJ Martín-Galiano - Frontiers in Immunology, 2021 - frontiersin.org
Vaccines and monoclonal antibodies are promising approaches for preventing and treating
infections caused by multidrug resistant Acinetobacter baumannii. However, only partial …

Combating tigecycline resistant Acinetobacter baumannii: A leap forward towards multi-epitope based vaccine discovery

S Ahmad, KE Ranaghan, SS Azam - European Journal of Pharmaceutical …, 2019 - Elsevier
Global emergence of Tigecycline resistant Acinetobacter baumannii (TRAB) is on the
horizon and poses a very serious threat to human health. There is a pressing demand for …