Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …

Pilewski, Joseph M., and Raymond A. Frizzell. Role of CFTR in Airway Disease. Physiol.
Rev. 79, Suppl.: S215–S255, 1999.—Cystic fibrosis (CF) is caused by mutations in the gene …

Cellular ion-transport processes depend on the availability of ATP generated through
metabolic processes. The effects of inhibition of active cellular metabolism have only been …

There have recently been important advances in our understanding of the molecular
structure and regulation of l3-adrenoceptors, which have implications for the elucidating l3 …

This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR) protein, an epithelial chloride channel expressed in the airways, pancreas, testis …

For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay
for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway …

To determine whether subjects with mild asthma or seasonal rhinitis have greater
bronchomotor responses to sulfur dioxide (SO2) than normal subjects, we undertook a study …

The anticholinergic, antimuscarinic compounds are potent and hitherto neglected
bronchodilators. Although atropine itself has drawbacks, principally related to its rapid …

Fluid and macromolecule secretion by submucosal glands in mammalian airways is
believed to be important in normal airway physiology and in the pathophysiology of cystic …