Non-immunoglobulin E-mediated gastrointestinal food allergic disorders (non-IgE-GI-FA)
include food protein-induced enterocolitis syndrome (FPIES), food protein-induced …

Down syndrome (DS) is the most common genetic disease and presents with cognitive
impairment, cardiac and gastrointestinal abnormalities, in addition to other miscellaneous …

Improvements in medical interventions for people with Down's syndrome have led to a
substantial increase in their longevity. Diagnosis and treatment of neurological …

This chapter reviews the neurological phenotype of Down syndrome (DS) in early
development, childhood, and aging. Neuroanatomic abnormalities in DS are manifested as …

Down syndrome (DS) is the most common genetic syndrome associated with immune
defects. The extent of immune dysregulation in DS is substantial, spanning the innate and …

OBJECTIVE: We describe patient characteristics and postoperative morbidity and mortality
rates for patients with Down syndrome undergoing congenital heart disease surgery …

Down syndrome is the most common chromosomal abnormality among live-born infants.
Through full or partial trisomy of chromosome 21, Down syndrome is associated with …

The thymus plays a fundamental role in establishing and maintaining central and peripheral
tolerance and defects in thymic architecture or AIRE expression result in the development of …

Although more than 90% of children born with congenital heart disease (CHD) survive into
adulthood, patients face significantly higher and premature morbidity and mortality. Heart …

Children with Down syndrome (DS) develop more infections, have an increased mortality
from sepsis and an increased incidence of chronic inflammatory conditions. Cytokine …